公开(公告)号：US09918665B2

公开(公告)日：2018-03-20

申请号：US14147263

申请日：2014-01-03

申请人： Nitto Denko Corporation

发明人： Stuart McRae ,  Wendy E. Bowerman ,  Stephen Wilson Braun ,  Regina Spiehl ,  Bernadette Messier ,  David Farquhar ,  Erin Koch Henkel ,  Jeremiah Peter O'Leary ,  Mark James Fisher ,  Uros Kascak ,  Loren J. Lantz ,  Zoran Novakovic ,  Jonathan Eppstein

IPC分类号： A61B5/00 ,  A61B5/145 ,  A61B5/15 ,  A61N1/30 ,  A61N1/32 ,  A61N1/04 ,  A61M37/00

CPC分类号： A61B5/14503 ,  A61B5/14532 ,  A61B5/15 ,  A61B5/685 ,  A61M2037/0007 ,  A61N1/0428 ,  A61N1/303 ,  A61N1/327

摘要： A transdermal permeant delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.