公开(公告)号：US11560425B2

公开(公告)日：2023-01-24

申请号：US16626625

申请日：2018-06-27

申请人： Neuracle Science Co., Ltd.

发明人： Bongcheol Kim ,  Eun Bee Cho ,  Dong Sik Kim ,  Jae-Keun Lee ,  Soon-gu Kwon ,  Jae Young Seong ,  Juwon Shim ,  Tae Woo Kim ,  Shin-hyuk Kang

IPC分类号： C07K16/24 ,  C07K16/30 ,  A61P35/00 ,  A61K45/06 ,  A61K39/00 ,  C07K16/28 ,  A61K39/395

摘要： The present disclosure relates to the pharmaceutical use of antagonists (e.g., an antibody or antigen-binding portion thereof) that specifically bind to FAM19A5 to promote a blood vessel normalization and treat a disease (e.g., cancer) in a subject in need thereof, e.g., by promoting a blood vessel normalization.