公开(公告)号：US20250011333A1

公开(公告)日：2025-01-09

申请号：US18394122

申请日：2023-12-22

Applicant: Nerviano Medical Sciences S. R. L.

Inventor： Gabriella TRAQUANDI ,  Maria Gabriella Brasca ,  Roberto D'Alessio ,  Paolo Polucci ,  Fulvia Roletto ,  Anna Vulpetti ,  Palolo Pevarello ,  Achille Panzeri ,  Francesca Quartieri ,  Ron Ferguson ,  Paola Vianello ,  Daniele Fancelli

IPC: C07D487/14 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/551 ,  C07D231/56 ,  C07D239/72 ,  C07D401/10 ,  C07D403/14 ,  C07D413/14 ,  C07D487/04

Abstract: Pyrazolo-quinazoline derivatives of formula (Ia) or (Ib) as defined in the specification, and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.