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    Use of molt-accelerating compounds, ecdysteroids, analogs thereof, and chitin synthesis inhibitors for controlling termites
    1.
    发明授权
    Use of molt-accelerating compounds, ecdysteroids, analogs thereof, and chitin synthesis inhibitors for controlling termites 有权
    使用蜕皮加速化合物，蜕皮类固醇，其类似物和几丁质合成抑制剂来控制白蚁

    公开(公告)号：US07998496B2

    公开(公告)日：2011-08-16

    申请号：US10589770

    申请日：2005-02-17

    申请人： Nan-Yao Su ,  James Edward King ,  Paul Allen Neese

    发明人： Nan-Yao Su ,  James Edward King ,  Paul Allen Neese

    IPC分类号： A01N25/32

    CPC分类号： A01N47/34 ,  A01N43/90 ,  A01N45/00 ,  A01N61/00 ,  Y10S424/11 ,  A01N37/28 ,  A01N25/006 ,  A01N37/40 ,  A01N43/16 ,  A01N49/00 ,  A01N2300/00

    摘要： The subject invention relates in part to the oral administration of ecdysteroids for controlling subterranean termites. Preferred ecdysteroids for use according to the subject invention are ecdysone, certain ecdysone analogs, and 20-hydroxyecdysone, for example. In some preferred embodiments, one or more of these compounds is used in a termite bait in combination with one or more chitin synthesis inhibitors (CSI), such as hexaflumuron and/or noviflumuron. The subject invention also relates to mixtures comprising these two active ingredients. The ecdysteroid analog or molt-accelerating compound (MAC) typically induces a preliminary molting event in termite workers, which then allows the CSI to further disrupt the molt and cause mortality. The combination of these active ingredients, causing accelerated molting together with inhibition of chitin synthesis, is surprisingly shown herein to enhance activity against termites, as compared to either group of compounds alone.

    摘要翻译： 本发明部分涉及用于控制地下白蚁的蜕皮甾酮的口服给药。 根据本发明使用的优选蜕皮类固醇类例如是蜕皮激素，某些蜕皮激素类似物和20-羟基蜕皮激素。 在一些优选的实施方案中，这些化合物中的一种或多种与白蚁诱饵结合使用一种或多种几丁质合成抑制剂（CSI），例如六氟呋喃和/或异氟脲。 本发明还涉及包含这两种活性成分的混合物。 蜕皮类固醇类似物或蜕皮加速化合物（MAC）通常诱导白蚁工作者的初步蜕皮事件，然后允许CSI进一步破坏蜕皮并引起死亡。 与单独的化合物组相比，这些活性成分的组合，引起加速蜕皮在一起，抑制几丁质合成，在本文中令人惊讶地显示出增强对白蚁的活性。

    Use of molt-accelerating compounds, ecdysteroids, analogs thereof, and chitin synthesis inhibitors for controlling termites
    2.
    发明授权
    Use of molt-accelerating compounds, ecdysteroids, analogs thereof, and chitin synthesis inhibitors for controlling termites 有权
    使用蜕皮加速化合物，蜕皮类固醇，其类似物和几丁质合成抑制剂来控制白蚁

    公开(公告)号：US08293797B2

    公开(公告)日：2012-10-23

    申请号：US13082915

    申请日：2011-04-08

    申请人： Nan-Yao Su ,  James Edward King ,  Paul Allen Neese

    发明人： Nan-Yao Su ,  James Edward King ,  Paul Allen Neese

    IPC分类号： A01N37/18

    CPC分类号： A01N47/34 ,  A01N43/90 ,  A01N45/00 ,  A01N61/00 ,  Y10S424/11 ,  A01N37/28 ,  A01N25/006 ,  A01N37/40 ,  A01N43/16 ,  A01N49/00 ,  A01N2300/00

    摘要： The subject invention relates in part to the oral administration of ecdysteroids for controlling subterranean termites. Preferred ecdysteroids for use according to the subject invention are ecdysone, certain ecdysone analogs, and 20-hydroxyecdysone, for example. In some preferred embodiments, one or more of these compounds is used in a termite bait in combination with one or more chitin synthesis inhibitors. Thus, the subject invention also relates in part to controlling termites by the use of a chitin synthesis inhibitor (CSI), such as hexaflumuron and/or noviflumuron, together with an ecdysteroid (and analogs thereof) or molt-accelerating compound (MAC), such as halofenozide. The subject invention also relates to mixtures comprising these two active ingredients. The MAC/ecdysteroid analog induces a preliminary molting event in termite workers (they could not complete the molting), which then allows the CSI to further disrupt the molt and cause mortality. The combination of these active ingredients, causing accelerated molting together with inhibition of chitin synthesis, is surprisingly shown herein to enhance activity against termites, as compared to either group of compounds alone.

    摘要翻译： 本发明部分涉及用于控制地下白蚁的蜕皮甾酮的口服给药。 根据本发明使用的优选蜕皮类固醇类例如是蜕皮激素，某些蜕皮激素类似物和20-羟基蜕皮激素。 在一些优选的实施方案中，这些化合物中的一种或多种与一种或多种几丁质合成抑制剂组合用于白蚁诱饵中。 因此，本发明还部分地涉及通过使用几丁质合成抑制剂（CSI），例如六氟隆和/或noviflumuron以及蜕皮类固醇（及其类似物）或蜕皮加速化合物（MAC）来控制白蚁， 例如卤代酰肼。 本发明还涉及包含这两种活性成分的混合物。 MAC /蜕皮类固醇模拟物引起白蚁工作者的初步蜕皮事件（他们不能完成蜕皮），然后允许CSI进一步破坏蜕皮并导致死亡。 与单独的化合物组相比，这些活性成分的组合，引起加速蜕皮在一起，抑制几丁质合成，在本文中令人惊讶地显示出增强对白蚁的活性。

    Use of Molt-Accelerating Compounds, Ecdysteroids, Analogs Thereof, and Chitin Synthesis Inhibitors for Controlling Termites
    3.
    发明申请
    Use of Molt-Accelerating Compounds, Ecdysteroids, Analogs Thereof, and Chitin Synthesis Inhibitors for Controlling Termites 有权
    使用催化加速化合物，蜕皮类固醇，其类似物和几丁质合成抑制剂用于控制白蚁

    公开(公告)号：US20110189122A1

    公开(公告)日：2011-08-04

    申请号：US13082915

    申请日：2011-04-08

    申请人： Nan-Yao SU ,  James Edward King ,  Paul Allen Neese

    发明人： Nan-Yao SU ,  James Edward King ,  Paul Allen Neese

    IPC分类号： A01N37/18 ,  A01N47/28 ,  A01N43/16 ,  A01N43/40 ,  A01N25/00 ,  A01N45/00 ,  A01P7/04

    CPC分类号： A01N47/34 ,  A01N43/90 ,  A01N45/00 ,  A01N61/00 ,  Y10S424/11 ,  A01N37/28 ,  A01N25/006 ,  A01N37/40 ,  A01N43/16 ,  A01N49/00 ,  A01N2300/00

    摘要： The subject invention relates in part to the oral administration of ecdysteroids for controlling subterranean termites. Preferred ecdysteroids for use according to the subject invention are ecdysone, certain ecdysone analogs, and 20-hydroxyecdysone, for example. In some preferred embodiments, one or more of these compounds is used in a termite bait in combination with one or more chitin synthesis inhibitors. Thus, the subject invention also relates in part to controlling termites by the use of a chitin synthesis inhibitor (CSI), such as hexaflumuron and/or noviflumuron, together with an ecdysteroid (and analogs thereof) or molt-accelerating compound (MAC), such as halofenozide. The subject invention also relates to mixtures comprising these two active ingredients. The MAC/ecdysteroid analog induces a preliminary molting event in termite workers (they could not complete the molting), which then allows the CSI to further disrupt the molt and cause mortality. The combination of these active ingredients, causing accelerated molting together with inhibition of chitin synthesis surprisingly shown herein to enhance activity against termites, as compared to either group of compounds alone.

    摘要翻译： 本发明部分涉及用于控制地下白蚁的蜕皮甾酮的口服给药。 根据本发明使用的优选蜕皮类固醇类例如是蜕皮激素，某些蜕皮激素类似物和20-羟基蜕皮激素。 在一些优选的实施方案中，这些化合物中的一种或多种与一种或多种几丁质合成抑制剂组合用于白蚁诱饵中。 因此，本发明还部分地涉及通过使用几丁质合成抑制剂（CSI），例如六氟隆和/或noviflumuron以及蜕皮类固醇（及其类似物）或蜕皮加速化合物（MAC）来控制白蚁， 例如卤代酰肼。 本发明还涉及包含这两种活性成分的混合物。 MAC /蜕皮类固醇模拟物引起白蚁工作者的初步蜕皮事件（他们不能完成蜕皮），然后允许CSI进一步破坏蜕皮并导致死亡。 与单独的一组化合物相比，这些活性成分的组合导致加速蜕皮在一起，抑制几丁质合成，这在本文中令人惊讶地显示出来，以提高对白蚁的活性。

    Use of Molt-Accelerating Compounds, Ecdysteroids, Analogs Thereof, and Chitin Synthesis Inhibitors for Controlling Termites
    4.
    发明申请
    Use of Molt-Accelerating Compounds, Ecdysteroids, Analogs Thereof, and Chitin Synthesis Inhibitors for Controlling Termites 有权
    使用催化加速化合物，蜕皮类固醇，其类似物和几丁质合成抑制剂用于控制白蚁

    公开(公告)号：US20080242647A1

    公开(公告)日：2008-10-02

    申请号：US10589770

    申请日：2005-02-17

    申请人： Nan-Yao Su ,  James Edward King ,  Paul Allen Neese

    发明人： Nan-Yao Su ,  James Edward King ,  Paul Allen Neese

    IPC分类号： A01N45/00 ,  A01P7/04

    CPC分类号： A01N47/34 ,  A01N43/90 ,  A01N45/00 ,  A01N61/00 ,  Y10S424/11 ,  A01N37/28 ,  A01N25/006 ,  A01N37/40 ,  A01N43/16 ,  A01N49/00 ,  A01N2300/00

    摘要： The subject invention relates in part to the oral administration of ecdysteroids for controlling subterranean termites. Preferred ecdysteroids for use according to the subject invention are ecdysone, certain ecdysone analogs, and 20-hydroxyecdysone, for example. In some preferred embodiments, one or more of these compounds is used in a termite bait in combination with one or more chitin synthesis inhibitors (CSI), such as hexaflumuron and/or noviflumuron. The subject invention also relates to mixtures comprising these two active ingredients. The ecdysteroid analog or molt-accelerating compound (MAC) typically induces a preliminary molting event in termite workers, which then allows the CSI to further disrupt the molt and cause mortality. The combination of these active ingredients, causing accelerated molting together with inhibition of chitin synthesis, is surprisingly shown herein to enhance activity against termites, as compared to either group of compounds alone.

    摘要翻译： 本发明部分涉及用于控制地下白蚁的蜕皮甾酮的口服给药。 根据本发明使用的优选蜕皮类固醇类例如是蜕皮激素，某些蜕皮激素类似物和20-羟基蜕皮激素。 在一些优选的实施方案中，这些化合物中的一种或多种与白蚁诱饵结合使用一种或多种几丁质合成抑制剂（CSI），例如六氟呋喃和/或异氟脲。 本发明还涉及包含这两种活性成分的混合物。 蜕皮类固醇类似物或蜕皮加速化合物（MAC）通常诱导白蚁工作者的初步蜕皮事件，然后允许CSI进一步破坏蜕皮并引起死亡。 与单独的化合物组相比，这些活性成分的组合，引起加速蜕皮在一起，抑制几丁质合成，在本文中令人惊讶地显示出增强对白蚁的活性。