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公开(公告)号:US20220389112A1
公开(公告)日:2022-12-08
申请号:US17774276
申请日:2020-11-06
发明人: Michael O'DWYER , John DALY , Sarkar SUBHASHIS
IPC分类号: C07K16/28 , A61K31/203 , C12N9/24 , A61K35/17 , A61P35/00
摘要: Provided is an effective amount of a desialylation agent and an effective amount of an anti CD38 antibody for use in the treatment of multiple myeloma. This results in potentiated primary NK cell activity against the multiple myeloma cell. Also envisaged is a method of treating multiple myeloma in a subject in need thereof.