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公开(公告)号:US10087447B2
公开(公告)日:2018-10-02
申请号:US14590397
申请日:2015-01-06
Applicant: NANYANG TECHNOLOGICAL UNIVERSITY
Inventor: Nguan Soon Tan , Han Chung Chong , Ming Jie Tan , Royston Huang
IPC: C12N15/113 , C07K16/22 , A61K39/00
Abstract: The invention provides an antibody specific to the ANGPTL4 protein capable of neutralizing proliferation and methods of making and using the same. The antibody of the invention is further directed to the C terminal region of the protein and may be capable of neutralizing cell proliferation and treating cancer. The antibody may be monoclonal and/or humanized antibody.