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公开(公告)号:US20160317647A1
公开(公告)日:2016-11-03
申请号:US15089050
申请日:2016-04-01
Applicant: Moderna Therapeutics, Inc.
Inventor: Giuseppe Ciaramella , Axel Bouchon , Eric Yi-Chun Huang
IPC: A61K39/155 , A61K9/00 , A61K39/39
CPC classification number: A61K39/145 , A61K9/0019 , A61K9/1271 , A61K9/5123 , A61K9/5146 , A61K31/7105 , A61K39/12 , A61K39/155 , A61K39/39 , A61K48/00 , A61K2039/53 , A61K2039/545 , A61K2039/55555 , C12N7/00 , C12N2760/16122 , C12N2760/16134 , C12N2760/16234
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.
Abstract translation: 本发明涉及包含编码一种或多种抗原的多核苷酸分子的制备,制备和治疗用核糖核酸疫苗(NAV)的组合物和方法。
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公开(公告)号:US20170002060A1
公开(公告)日:2017-01-05
申请号:US15106000
申请日:2015-01-08
Applicant: MODERNA THERAPEUTICS, INC.
Inventor: Joseph Beene Bolen , Axel Bouchon , Giuseppe Ciaramella , Eric Yi-Chun Huang
IPC: C07K16/00
CPC classification number: C07K16/00 , A61K2039/505 , A61K2039/53
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding an antibody, variant or fragment.
Abstract translation: 本发明涉及用于制备,制造和治疗性使用编码抗体,变体或片段的多核苷酸的组合物和方法。
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公开(公告)号:US20160331828A1
公开(公告)日:2016-11-17
申请号:US15091123
申请日:2016-04-05
Applicant: Moderna Therapeutics, Inc.
Inventor: Giuseppe Ciaramella , Axel Bouchon , Eric Yi-Chun Huang
IPC: A61K39/145 , A61K9/127 , A61K9/51 , C12N7/00
CPC classification number: A61K39/145 , A61K9/0019 , A61K9/1271 , A61K9/5123 , A61K9/5146 , A61K31/7105 , A61K39/12 , A61K39/155 , A61K39/39 , A61K48/00 , A61K2039/53 , A61K2039/545 , A61K2039/55555 , C12N7/00 , C12N2760/16122 , C12N2760/16134 , C12N2760/16234
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.
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