公开(公告)号：US20170145202A1

公开(公告)日：2017-05-25

申请号：US15295636

申请日：2016-10-17

申请人： Miami University

发明人： Jessica L. Sparks ,  Martha M. Fitzgerald ,  Jason Berberich

IPC分类号： C08L33/26 ,  B29B7/32 ,  B33Y30/00 ,  B33Y70/00 ,  B29C67/00 ,  B33Y10/00

CPC分类号： C08L33/26 ,  B29B7/325 ,  B29B7/7457 ,  B29C64/00 ,  B29C64/106 ,  B29C64/129 ,  B29C64/20 ,  B29C64/40 ,  B29K2033/26 ,  B29K2105/0061 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y70/00 ,  C08F220/56 ,  C08F251/00 ,  C08J3/246 ,  C08J2333/26 ,  C08J2405/04 ,  C08K2003/265 ,  C08L2205/04 ,  C08F220/54 ,  C08F222/385

摘要： An alginate-polyacrylamide IPN hydrogel formulation for 3D printing using a dual syringe system where the components that initiate polymerization of each network remain separated until printing. The dual syringe system may use a single motor and mixing head to combine both parts of the hydrogel formulation for controlled polymerization of the material. The elastic and time-dependent viscoelastic properties (stress relaxation) are tuned to match mammalian tissues by changing the crosslink density and monomer concentration. The fracture energy of the material may be increased by soaking in a calcium chloride solution. The resulting IPN polymer material may find application in soft tissue medical simulation devices, particularly because the mechanical properties may be tuned to mimic the elastic and viscoelastic properties of muscle tissue and may be 3D printed in the shape of anatomical parts.