专利检索 ap:("MiNk Therapeutics, Inc.") AND inv:"Ekaterina Vladimirovna Breous-Nystrom" 第 1 页

1.

发明公开
T CELL RECEPTORS THAT BIND TO MIXED LINEAGE LEUKEMIA (MLL)-SPECIFIC PHOSPHOPEPTIDES AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：US20240301025A1

公开(公告)日：2024-09-12

申请号：US18340600

申请日：2023-06-23

申请人： MiNk Therapeutics, Inc.

发明人： Marc van Dijk , Ekaterina Vladimirovna Breous-Nystrom , Alessandra Franchino , Sébastien Lalevée , Arthur Andrew Hurwitz , Mark Adrian Exley , Benjamin Jacob Wolf

IPC分类号： C07K14/725 , A61K38/00 , A61K45/06 , C12N15/63

CPC分类号： C07K14/7051 , C12N15/63 , A61K38/00 , A61K45/06 , C07K2317/565

摘要： Provided are TCRs (e.g., TCRs that bind to MLL, e.g., TCRs that bind to an MLL phosphopeptide, e.g., TCRs that bind to an MLL phosphopeptide/MHC complex), cells and pharmaceutical compositions comprising these TCRs, nucleic acids encoding these TCRs, expression vectors and host cells for making these TCRs, and methods of treating a subject using these TCRs.

2.

发明授权
T cell receptors that bind to mixed lineage leukemia (MLL)-specific phosphopeptides and methods of use thereof 有权

公开(公告)号：US11718658B2

公开(公告)日：2023-08-08

申请号：US16807742

申请日：2020-03-03

申请人： MiNK Therapeutics, Inc.

发明人： Marc van Dijk , Ekaterina Vladimirovna Breous-Nystrom , Alessandra Franchino , Sébastien Lalevée , Arthur Andrew Hurwitz , Mark Adrian Exley , Benjamin Jacob Wolf

IPC分类号： C07K14/725 , C12N15/63 , A61K38/00 , A61K45/06

CPC分类号： C07K14/7051 , C12N15/63 , A61K38/00 , A61K45/06 , C07K2317/565

摘要： Provided are TCRs (e.g., TCRs that bind to MLL, e.g., TCRs that bind to an MLL phosphopeptide, e.g., TCRs that bind to an MLL phosphopeptide/MHC complex), cells and pharmaceutical compositions comprising these TCRs, nucleic acids encoding these TCRs, expression vectors and host cells for making these TCRs, and methods of treating a subject using these TCRs.