公开(公告)号：US20230192489A1

公开(公告)日：2023-06-22

申请号：US18172624

申请日：2023-02-22

申请人： Merck Sharp & Dohme LLC

发明人： Akhilesh Bhambhani ,  Muneeswara Babu Medi ,  Maya Salnikova ,  William James Smith ,  David S. Thiriot

IPC分类号： C01B25/36 ,  A61K47/52 ,  A61K39/39

CPC分类号： C01B25/36 ,  A61K47/52 ,  A61K39/39 ,  A61K2039/55505

摘要： Vaccine formulations are described comprising physically separated, lyophilized antigens and adjuvant components, which may be in lyoparticle form, as well as methods of using and making such formulations. Reconstituted formulations are also described.

公开(公告)号：US20230234850A1

公开(公告)日：2023-07-27

申请号：US18172695

申请日：2023-02-22

申请人： Merck Sharp & Dohme LLC

发明人： Akhilesh Bhambhani ,  Muneeswara Babu Medi ,  Maya Salnikova ,  William James Smith ,  David S. Thiriot

IPC分类号： C01B25/36 ,  A61K47/52 ,  A61K39/39

CPC分类号： C01B25/36 ,  A61K47/52 ,  A61K39/39 ,  A61K2039/55505

摘要： Vaccine formulations are described comprising physically separated, lyophilized antigens and adjuvant components, which may be in lyoparticle form, as well as methods of using and making such formulations. Reconstituted formulations are also described.