公开(公告)号：US10766883B2

公开(公告)日：2020-09-08

申请号：US16468465

申请日：2017-12-07

Applicant: Merck Sharp & Dohme Corp.

Inventor： Peter Fuller ,  Jason Brubaker ,  Hongbo Zeng ,  Joshua Close ,  Jonathan Young

IPC: C07D405/04 ,  C07D405/14

Abstract: The instant invention provides compounds which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

公开(公告)号：US20190330195A1

公开(公告)日：2019-10-31

申请号：US16468465

申请日：2017-12-07

Applicant: Merck Sharp & Dohme Corp.

Inventor： Peter Fuller ,  Jason Brubaker ,  Hongbo Zeng ,  Joshua Close ,  Jonathan Young

IPC: C07D405/04 ,  C07D405/14

Abstract: The instant invention provides compounds which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.