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公开(公告)号:US20030153600A1
公开(公告)日:2003-08-14
申请号:US10342380
申请日:2003-01-14
Applicant: Merck & Co., Inc.
Inventor: Louis S. Crocker , Ian W. Davies , Richard G. Osifchin , Andrew Kotliar
IPC: A61K031/444 , C07D41/04
CPC classification number: C07D213/61
Abstract: This invention encompasses the Form V polymorph of Compound A of structural formula: 1 which is useful in the treatment of cyclooxygenase-2 mediated diseases. The invention encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising the Form V polymorph of Compound A. The invention also encompasses a process for synthesizing the Form V polymorph of Compound A.