公开(公告)号：US20020177617A1

公开(公告)日：2002-11-28

申请号：US10106845

申请日：2002-03-26

Applicant: Merck & Co., Inc.

Inventor： Kremena Simitchieva ,  Scott A. Reines ,  Errol McKinney ,  Eric J. Sandquist ,  Deepak K. Khannna ,  Richard Hargreaves

IPC: A61K031/421 ,  A61K031/415

CPC classification number: A61K31/42 ,  A61K31/40 ,  A61K31/415 ,  A61K31/54 ,  A61K45/06 ,  A61K31/41 ,  A61K2300/00

Abstract: A combination of a 5HT1B/1D agonist and a COX-2 selective inhibitor is useful in the treatment and or prevention of migraine.