公开(公告)号：US20240293444A1

公开(公告)日：2024-09-05

申请号：US18653713

申请日：2024-05-02

Applicant: MedinCell S.A.

Inventor： Christophe ROBERGE ,  Adolfo LÓPEZ-NORIEGA ,  Jean-Manuel CROS ,  Juliette SERINDOUX ,  Murielle OSTER ,  Fang LIU ,  Charlotte MOLINIER ,  Sylvestre GRIZOT ,  Tjasa VRLINIC ,  Feifei NG ,  Elise GUÉGAIN ,  Marie-Emérentienne CAGNON

IPC: A61K31/765 ,  A61K9/00 ,  A61K31/445 ,  A61K31/4985 ,  A61K31/5415 ,  A61K31/675 ,  A61K31/7048 ,  A61K47/34

CPC classification number: A61K31/765 ,  A61K9/0024 ,  A61K31/445 ,  A61K31/4985 ,  A61K31/5415 ,  A61K31/675 ,  A61K31/7048 ,  A61K47/34

Abstract: The present invention provides a pharmaceutical composition comprising:
a biodegradable multi-branched copolymer comprising at least three polyester arms attached to a central core which comprises a polyether, and wherein the multi-branched copolymer is substantially insoluble in aqueous solution, further comprising at least one pharmaceutically active ingredient.

公开(公告)号：US20250009647A1

公开(公告)日：2025-01-09

申请号：US18294961

申请日：2022-08-05

Applicant: MedinCell S.A.

Inventor： Juliette SERINDOUX ,  Adolfo LÓPEZ-NORIEGA

IPC: A61K9/00 ,  A61K31/343 ,  A61K31/40 ,  A61K38/12 ,  A61K47/10 ,  A61K47/12 ,  A61K47/20 ,  A61K47/34

Abstract: The present invention provides a pharmaceutical composition comprising or consisting of at least one polyether-polyester copolymer, wherein the copolymer has the formula: B(A)n wherein B represents a polyether and comprises polyethylene glycol (PEG), each A represents a polyester arm and n is an integer from 1 to 8; at least one nucleophilic compound; at least one organic solvent; and up to 10% (w/w) of at least one acidic compound having a pKa(H2O) of less than 3.