公开(公告)号：US20210030321A1

公开(公告)日：2021-02-04

申请号：US17065510

申请日：2020-10-07

Applicant: Massachusetts Institute of Technology

Inventor： Vincent Hok Liu ,  Christophoros Christou Vassiliou ,  Yibo Ling ,  Michael J. Cima

IPC: A61B5/145 ,  A61B5/00 ,  G01R33/56 ,  A61K49/10

Abstract: A sensor is provided for measuring a dissolved oxygen concentration in vivo when implanted at a tissue site and in ex vivo applications. The sensor includes an article comprising a sensing medium retained within the implantable article by an oxygen-permeable material. The sensing medium comprises an MR contrast agent for oxygen. The sensor is configured to indicate the dissolved oxygen concentration of a fluid, e.g., in vivo at the tissue site, when subjected to an MR-based method.