公开(公告)号：US11964026B2

公开(公告)日：2024-04-23

申请号：US17892496

申请日：2022-08-22

Applicant: Massachusetts Institute of Technology

Inventor： Antonio Eric Barberio ,  Santiago Correa Echavarria ,  Mariane Bandeira Melo ,  Talar Tokatlian ,  Erik Christopher Dreaden ,  Paula T. Hammond ,  Darrell J. Irvine

IPC: A61K47/54 ,  A61K9/00 ,  A61K9/127 ,  A61K38/20 ,  A61K47/69 ,  A61P35/00

CPC classification number: A61K47/6911 ,  A61K9/0019 ,  A61K9/1271 ,  A61K38/208 ,  A61K47/544 ,  A61P35/00

Abstract: Disclosed are particles for delivering cytokinese, such as IL-12, for the treatment of cancer. The particles comprise cytokines non-covalently bound to liposomes, where the liposomes are coated with polyelectrolytes.

公开(公告)号：US20190125895A1

公开(公告)日：2019-05-02

申请号：US16175311

申请日：2018-10-30

Applicant: Massachusetts Institute of Technology

Inventor： Antonio Eric Barberio ,  Santiago Correa Echavarria ,  Mariane Bandeira Melo ,  Talar Tokatlian ,  Erik Christopher Dreaden ,  Paula T. Hammond ,  Darrell J. Irvine

IPC: A61K47/69 ,  A61P35/00 ,  A61K38/20 ,  A61K47/54

Abstract: Disclosed are particles for delivering cytokinese, such as IL-12, for the treatment of cancer. The particles comprise cytokines non-covalently bound to liposomes, where the liposomes are coated with polyelectrolytes.

公开(公告)号：US11419947B2

公开(公告)日：2022-08-23

申请号：US16175311

申请日：2018-10-30

Applicant: Massachusetts Institute of Technology

Inventor： Antonio Eric Barberio ,  Santiago Correa Echavarria ,  Mariane Bandeira Melo ,  Talar Tokatlian ,  Erik Christopher Dreaden ,  Paula T. Hammond ,  Darrell J. Irvine

IPC: A61K47/69 ,  A61K47/54 ,  A61K38/20 ,  A61P35/00 ,  A61K9/127 ,  A61K9/00

Abstract: Disclosed are particles for delivering cytokinese, such as IL-12, for the treatment of cancer. The particles comprise cytokines non-covalently bound to liposomes, where the liposomes are coated with polyelectrolytes.