公开(公告)号：US09157674B2

公开(公告)日：2015-10-13

申请号：US10562750

申请日：2004-07-01

申请人： Martin Collins ,  Jack Bailey ,  József Nagy

发明人： Martin Collins ,  Jack Bailey ,  József Nagy ,  Dan Joslin

IPC分类号： F25D11/02 ,  F25D23/02 ,  F25D17/06 ,  F25C1/24 ,  F25D21/08 ,  F25D21/14

CPC分类号： F25D17/062 ,  F25C1/24 ,  F25D17/067 ,  F25D21/08 ,  F25D21/14 ,  F25D23/026 ,  F25D2303/0822 ,  F25D2303/08222 ,  F25D2317/062 ,  F25D2317/0651 ,  F25D2317/0664 ,  F25D2317/0665 ,  F25D2317/067 ,  F25D2317/0672 ,  F25D2400/10

摘要： The present invention relates to a refrigerated air supply system (21) for a freezer and/or refrigerator cabinet having at least one cabinet compartment (17) at least partly defined by inner walls (16), an insulation layer at least partly enclosing the cabinet compartment. The cabinet compartment (17) has an compartment opening facing substantially upwards, which compartment opening connects the cabinet compartment (17) with the space surrounding the cabinet, the cabinet also including, a door which in one position covers the compartment opening and substantially encloses the cabinet compartment (17). The cabinet further includes a machine compartment (23) for storing at least a compressor, at least one of the inner walls (16) having a substantially horizontal shelf plane (52) where at least one of the planes (52) is being positioned vertically above the machine compartment (23).

摘要翻译： 本发明涉及一种用于冷冻和/或冰箱柜的冷藏空气供应系统（21），其具有至少部分地由内壁（16）限定的至少一个柜室（17），绝缘层至少部分地包围该柜 隔间 柜室（17）具有面向大致向上的隔室开口，该隔室开口将柜室（17）与围绕柜的空间连接，柜还包括门，该门在一个位置上覆盖隔室开口并基本上包围 柜室（17）。 所述机柜还包括用于至少存储压缩机的机舱（23），所述内壁（16）中的至少一个具有基本水平的搁架平面（52），其中所述平面（52）中的至少一个垂直地定位 在机舱（23）的上方。

公开(公告)号：US07435744B2

公开(公告)日：2008-10-14

申请号：US10761940

申请日：2004-01-21

申请人： Gyorgy Domány ,  Csilla Horváth ,  Gizella Bartáné Szalai ,  József Nagy ,  Sándor Kolok ,  Éva Kovácsné Bozó ,  István Borza ,  István Vágó ,  Attila Bielik ,  Györgyi Ignáczné Szendrei ,  György Keserü ,  Sándor Farkas

发明人： Gyorgy Domány ,  Csilla Horváth ,  Gizella Bartáné Szalai ,  József Nagy ,  Sándor Kolok ,  Éva Kovácsné Bozó ,  István Borza ,  István Vágó ,  Attila Bielik ,  Györgyi Ignáczné Szendrei ,  György Keserü ,  Sándor Farkas

IPC分类号： A61K31/445 ,  C07D401/12

CPC分类号： C07D211/14 ,  C07D211/16 ,  C07D401/12 ,  C07D413/12 ,  C07D417/12

摘要： The present invention relates to a compound of formula (I): wherein: V and U are hydrogen, halogen, C1-C4 alkylamino, or together form a group that contains one or more heteroatoms, and that taken together with one or more: (a) hydrogen atoms; (b) carbon atoms; (c) —CH═ groups; (d) —CH2— groups; or (e) additional heteroatoms of the same or different type; or any combination thereof, form a 4-7 membered homocyclic or heterocyclic ring, wherein the homocyclic or heterocyclic ring may combine with the phenyl group to form a bicyclic ring, and wherein the homocyclic or heterocyclic ring or the bicyclic ring may contain one or more oxo, thioxo, amino, mercapto, trifluoromethyl, C1-C4 alkyl, ═S or —SH groups; W: is —CO—, —CH2— or —CH2—(C1-C4 alkyl)-; X: is —CO—; Y: is —O—, C1-C4 alkylene, C1-C4 alkynylene, cycloalkylene, aminocarbonyl, —NH—, —N(C1-C4 alkyl)-, -C1-C4 alkylene-N(C1-C4 alkyl)-, —CH2O—, —CH(OH)— or —OCH2—; Z: is hydrogen, halogen, nitro, amino, C1-C4 alkyl, C1-C4 alkoxy, cyano, trifluoromethyl, hydroxyl or carboxyl; R1 and R2: are hydrogen, or together form a C1-C3 bridge; and n and m: independently are 0-3, wherein n and m cannot each be 0; or an optical antipode, racemate or pharmaceutically-acceptable salt thereof. The carboxylic acid amide derivatives of formula (I) are highly effective and selective antagonists of the NMDA receptor.