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公开(公告)号：US11225672B2
公开(公告)日：2022-01-18
申请号：US16658892
申请日：2019-10-21
发明人： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Krishnakumar Sridharan
IPC分类号： C12N15/82 , C07K14/195 , A01N37/46 , C07K14/32 , A01N63/50
摘要： A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.
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公开(公告)号：US20180291395A1
公开(公告)日：2018-10-11
申请号：US15944114
申请日：2018-04-03
发明人： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Krishnakumar Sridharan
IPC分类号： C12N15/82 , C07K14/415 , C07K14/47 , C07K14/32 , C07K14/245 , C07K14/27 , C07K14/26
摘要： A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.
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公开(公告)号：US20240352480A1
公开(公告)日：2024-10-24
申请号：US18628578
申请日：2024-04-05
发明人： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Krishnakumar Sridharan
IPC分类号： C12N15/82 , A01N37/46 , A01N63/50 , C07K14/195 , C07K14/32
CPC分类号： C12N15/8286 , A01N37/46 , A01N63/50 , C07K14/195 , C07K14/32 , C07K2319/00
摘要： A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.
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公开(公告)号：US11859191B2
公开(公告)日：2024-01-02
申请号：US17817196
申请日：2022-08-03
IPC分类号： C12N15/82
CPC分类号： C12N15/8213 , C12N15/8205 , C12N2310/20 , C12N2800/80
摘要： This disclosure is related to plant-optimized recombinant nucleic acids encoding Cpf1 and their use in planta. Also disclosed are compositions, expression cassettes, and plant cells comprising the recombinant nucleic acids as well as methods and kits for modifying a target sequence in a plant genome using the recombinant nucleic acids.
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公开(公告)号：US11414669B2
公开(公告)日：2022-08-16
申请号：US16563581
申请日：2019-09-06
IPC分类号： C12N15/82
摘要： This disclosure is related to plant-optimized recombinant nucleic acids encoding Cpf1 and their use in planta. Also disclosed are compositions, expression cassettes, and plant cells comprising the recombinant nucleic acids as well as methods and kits for modifying a target sequence in a plant genome using the recombinant nucleic acids.
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公开(公告)号：US20220235369A1
公开(公告)日：2022-07-28
申请号：US17575318
申请日：2022-01-13
发明人： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flainski , Arlene R. Howe , Krishnakumar Sridharan
IPC分类号： C12N15/82 , A01N37/46 , C07K14/195 , C07K14/32 , A01N63/50
摘要： A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.
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公开(公告)号：US10465205B2
公开(公告)日：2019-11-05
申请号：US15944114
申请日：2018-04-03
发明人： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Krishnakumar Sridharan
IPC分类号： C12N15/82 , C07K14/195 , C07K14/32 , A01N37/46 , A01N63/02
摘要： A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.
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公开(公告)号：US11981908B2
公开(公告)日：2024-05-14
申请号：US17575318
申请日：2022-01-13
发明人： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Krishnakumar Sridharan
IPC分类号： C12N15/82 , A01N37/46 , A01N63/50 , C07K14/195 , C07K14/32
CPC分类号： C12N15/8286 , A01N37/46 , A01N63/50 , C07K14/195 , C07K14/32 , C07K2319/00 , A01N63/50 , A01N63/20
摘要： A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.
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