公开(公告)号：US20180303780A1

公开(公告)日：2018-10-25

申请号：US15566955

申请日：2016-04-14

申请人： METABRAIN RESEARCH

发明人： Sophie N. RAYNAL ,  Micheline R. KERGOAT ,  Valerie AUTIER ,  Christine G. CHARON ,  Jean-Denis DURAND ,  Franck F. LEPIFRE ,  Annick M. AUDET

IPC分类号： A61K31/197 ,  A61K31/4402 ,  A61K31/4406 ,  A61K31/50 ,  A61K31/216 ,  A61K31/165 ,  A61P21/00

CPC分类号： A61K31/197 ,  A61K31/15 ,  A61K31/165 ,  A61K31/216 ,  A61K31/4402 ,  A61K31/4406 ,  A61K31/495 ,  A61K31/50 ,  A61P21/00

摘要： This invention relates to a derivative of the general formula (I), as follows: or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof for use as a medicament for the treatment and/or prevention of muscle atrophy in mammals and/or for limiting muscular atrophy in mammals and/or to promote muscle growth in exercising mammals aimed at increasing muscle mass and quality, preventing the occurrence of symptoms of sarcopenia related to age or rehabilitation after a muscle loss, age-related muscle atrophy and/or the consequences of drug therapy and/or immobilization and/or cachexia.