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公开(公告)号：US20150275220A1
公开(公告)日：2015-10-01
申请号：US14432361
申请日：2013-10-02
申请人： Lipocalyx GmbH
IPC分类号： C12N15/64 , C08G81/00 , C08L79/02 , C12N15/113 , C08K5/205 , C08F8/18 , C08L39/02 , C08L39/00 , C12N15/85 , C08G73/02 , C08F8/14
CPC分类号： C12N15/64 , A61K47/542 , A61K47/543 , A61K47/59 , A61K47/645 , C08F8/14 , C08F8/18 , C08G73/0206 , C08G81/00 , C08K5/205 , C08L39/00 , C08L39/02 , C08L79/02 , C08L2203/02 , C12N15/1137 , C12N15/85 , C12N2310/14 , C12N2310/351 , C12N2800/107
摘要： The invention provides polyamine derivatives, a use of the polyamine derivatives for the transfection of polyanions into cells, and a method of transfecting cells with a polyanion, comprising mixing said polyanion with a polyamine derivative e.g. in a buffer and treating said cells with the mixture obtained in the previous step.
摘要翻译： 本发明提供多胺衍生物，多胺衍生物用于将聚阴离子转染到细胞中的用途，以及用聚阴离子转染细胞的方法，包括将所述聚阴离子与多胺衍生物例如 在缓冲液中并用前一步骤获得的混合物处理所述细胞。
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公开(公告)号：US09677073B2
公开(公告)日：2017-06-13
申请号：US14432327
申请日：2013-10-02
申请人： Lipocalyx GmbH
IPC分类号： C12N15/113 , C08G73/02 , C08L79/02 , C12N15/85 , A61K47/48
CPC分类号： C12N15/113 , A61K47/543 , A61K47/59 , A61K47/645 , C08G73/0206 , C08L79/02 , C08L2203/02 , C12N15/85 , C12N2310/14 , C12N2310/351 , C12N2800/107
摘要： The invention provides hydroxylated polyamine derivatives, their use for the transfection of polyanions into cells, and a method of transfecting cells with a polyanion, comprising mixing said polyanion with said hydroxylated polyamine derivative in a buffer and treating said cells with the mixture obtained in the previous step.
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公开(公告)号：US09677078B2
公开(公告)日：2017-06-13
申请号：US14432361
申请日：2013-10-02
申请人： Lipocalyx GmbH
IPC分类号： C12N15/64 , C08F8/14 , C08F8/18 , C08G73/02 , C08G81/00 , C08K5/205 , C08L39/00 , C08L39/02 , C12N15/113 , C12N15/85 , A61K47/48 , C08L79/02
CPC分类号： C12N15/64 , A61K47/542 , A61K47/543 , A61K47/59 , A61K47/645 , C08F8/14 , C08F8/18 , C08G73/0206 , C08G81/00 , C08K5/205 , C08L39/00 , C08L39/02 , C08L79/02 , C08L2203/02 , C12N15/1137 , C12N15/85 , C12N2310/14 , C12N2310/351 , C12N2800/107
摘要： The invention provides polyamine derivatives, a use of the polyamine derivatives for the transfection of polyanions into cells, and a method of transfecting cells with a polyanion, comprising mixing said polyanion with a polyamine derivative e.g. in a buffer and treating said cells with the mixture obtained in the previous step.
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公开(公告)号：US20150259678A1
公开(公告)日：2015-09-17
申请号：US14432327
申请日：2013-10-02
申请人： LIPOCALYX GMBH
IPC分类号： C12N15/113 , C08G73/02 , C08L79/02 , C12N15/85
CPC分类号： C12N15/113 , A61K47/543 , A61K47/59 , A61K47/645 , C08G73/0206 , C08L79/02 , C08L2203/02 , C12N15/85 , C12N2310/14 , C12N2310/351 , C12N2800/107
摘要： The invention provides hydroxylated polyamine derivatives, their use for the transfection of polyanions into cells, and a method of transfecting cells with a polyanion, comprising mixing said polyanion with said hydroxylated polyamine derivative in a buffer and treating said cells with the mixture obtained in the previous step.
摘要翻译： 本发明提供了羟基化多胺衍生物，其用于将聚阴离子转染入细胞的用途，以及用聚阴离子转染细胞的方法，包括将所述聚阴离子与所述羟基化多胺衍生物混合在缓冲液中，并用前面得到的混合物处理所述细胞 步。
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