公开(公告)号：US20180298453A1

公开(公告)日：2018-10-18

申请号：US15947750

申请日：2018-04-06

Applicant: Life Technologies Corporation

Inventor： Rixun FANG ,  Manohar FURTADO ,  Manfred KAYSER ,  Kaye BALLANTYNE

IPC: C12Q1/6888

Abstract: The methods and compositions provided herein relate to the discovery of 13 STR markers, found on the human Y chromosome, having surprisingly high mutation rates when compared with 173 other Y-STR markers known today. The set of RM-Y-STRs may overcome the current dilemma of Y-chromosome analysis in forensic applications due to their extraordinary mutation properties. Embodiments of the invention include methods for allelic determination of rapidly-mutating Y-STR markers, amplification primers for the analysis of rapidly-mutating Y-STR markers, allelic ladders for analysis of rapidly-mutating Y-STR markers, and kits for the analysis of rapidly-mutating Y-STR markers.