-
1.发明授权Pharmaceutical aerosol formulation comprising a medicament, a propellant and a fluorinated surfactant 失效药物气溶胶制剂，其包含药物，推进剂和氟化表面活性剂
公开(公告)号：US5849265A
公开(公告)日：1998-12-15
申请号：US809764
申请日：1997-03-27
申请人： Li Li-Bovet , Keith A. Johnson
发明人： Li Li-Bovet , Keith A. Johnson
IPC分类号： A61K9/12 , A61K9/00 , A61K9/72 , A61K47/06 , B01F17/20 , C07F9/09 , C07F9/10 , A61L9/04 , A61K31/135 , A61K31/35 , A61K31/52 , A61K31/56
CPC分类号： A61K9/008 , C07F9/10 , Y10S514/975
摘要： A pharmaceutical aerosol formulation which comprises particulate medicament, a fluorocarbon of hydrogen-containing chlorofluorocarbon propellant and a surfactant of general formula (I), wherein n is an integer of 1 to 18; m is an integer of 0 to 17; and R.sup.1, R.sup.2 and R.sup.3 are each independently a hydrogen atom or a C.sub.1-4 alkyl group.
摘要翻译： PCT No.PCT / IB95 / 00866 Sec。 371日期1997年3月27日 102（e）1997年3月27日PCT PCT 1995年9月27日PCT公布。 出版物WO96 / 09816 （I）一种药物气溶胶制剂，其包含颗粒药物，含氢氯氟烃推进剂的氟碳化合物和通式（I）的表面活性剂，其中n为1至18的整数; m为0〜17的整数。 并且R 1，R 2和R 3各自独立地为氢原子或C 1-4烷基。
-
2.发明授权公开(公告)号：US06558651B1
公开(公告)日：2003-05-06
申请号：US09091496
申请日：1998-06-18
IPC分类号： A61K912
摘要： This invention relates to aerosol formulations of use for the administration of medicaments by inhalation. More particularly, the invention relates to a pharmaceutical aerosol formulation which comprises particulate salbutamol sulphate having a crystalline form in which the outer layer of the crystals is substantially non-amorphous; and 1,1,1,2-tetrafluoroethane. A method of treating respiratory disorders which comprises administration by inhalation of an effective amount of a pharmaceutical aerosol formulation as defined is also described.
摘要翻译： 本发明涉及用于通过吸入给药药物的气溶胶制剂。 更具体地，本发明涉及一种药物气溶胶制剂，其包含具有结晶形式的颗粒状沙丁胺醇硫酸盐，其中所述晶体的外层基本上是非无定形的; 和1,1,1,2-四氟乙烷。 还描述了一种治疗呼吸系统疾病的方法，其包括通过吸入有效量的如所定义的药物气雾剂制剂给药。
-
公开(公告)号：US06546928B1
公开(公告)日：2003-04-15
申请号：US09570725
申请日：2000-05-15
申请人： Ian C. Ashurst , Ignatius Loy Britto , Craig Steven Herman , Li Li-Bovet , Michael Thomas Riebe
发明人： Ian C. Ashurst , Ignatius Loy Britto , Craig Steven Herman , Li Li-Bovet , Michael Thomas Riebe
IPC分类号： A61M1100
CPC分类号： B65D83/54 , A61M15/009 , A61M2205/0222
摘要： A metered dose inhaler having all or part of its internal surfaces coated with one or more fluorocarbon polymers, optimally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formation comprising albuterol or a physiologically acceptable salt thereof and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.
摘要翻译： 一种计量吸入器，其全部或部分内表面涂覆有一种或多种氟碳聚合物，最佳地与一种或多种非碳氟聚合物组合，用于分配包含沙丁胺醇或其生理学上可接受的盐和氟碳推进剂的吸入药物形式 任选地与一种或多种其它药理活性剂或一种或多种赋形剂组合。
-
公开(公告)号：US6131566A
公开(公告)日：2000-10-17
申请号：US831268
申请日：1997-03-31
IPC分类号： A61K9/00 , A61K9/12 , A61K9/72 , A61K31/135 , A61K31/137 , A61K31/57 , A61K31/573 , A61M15/00 , A61P11/08 , B05D5/08 , B05D7/22 , B05D7/24 , B65D83/14 , A61M11/00
CPC分类号： A61K9/008 , A61K31/137 , A61K31/57 , A61K31/573 , A61K9/124 , A61M15/009 , B65D83/54 , A61M2205/0222
摘要： A metered dose inhaler having all or part of its internal surfaces coated with one or more fluorocarbon polymers, optimally a blend of one or more fluorocarbon polymers in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formation comprising albuterol or a physiologically acceptable salt thereof and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.
摘要翻译： 一种计量吸入器，其具有涂覆有一种或多种氟碳聚合物的全部或部分内表面，最佳地是一种或多种氟碳聚合物与一种或多种非氟碳聚合物组合的共混物，用于分配包含沙丁胺醇或 其生理上可接受的盐和碳氟化合物推进剂，任选地与一种或多种其它药理学活性剂或一种或多种赋形剂组合。
-
公开(公告)号：US06532955B1
公开(公告)日：2003-03-18
申请号：US09570789
申请日：2000-05-15
申请人： Ian C. Ashurst , Ignatius Loy Britto , Craig Steven Herman , Li Li-Bovet , Michael Thomas Riebe
发明人： Ian C. Ashurst , Ignatius Loy Britto , Craig Steven Herman , Li Li-Bovet , Michael Thomas Riebe
IPC分类号： A61M1100
CPC分类号： A61K9/008 , A61K9/124 , A61K31/137 , A61K31/57 , A61K31/573 , A61M15/009 , A61M2205/0222 , B65D83/54 , A61K31/135 , A61K2300/00
摘要： A metered dose inhaler having all or part of its internal surfaces coated with one or more fluorocarbon polymers, optimally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formation comprising fluticasone propionate or a physiologically acceptable solvate thereof and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.
摘要翻译： 一种计量吸入器，其全部或部分内表面涂覆有一种或多种碳氟聚合物，最佳地与一种或多种非碳氟聚合物组合，用于分配包含丙酸氟替卡松或其生理学上可接受的溶剂合物的吸入药物形式，以及碳氟化合物 推进剂，任选地与一种或多种其它药理活性剂或一种或多种赋形剂组合。
-
公开(公告)号：US06524555B1
公开(公告)日：2003-02-25
申请号：US09562946
申请日：2000-05-03
申请人： Ian C. Ashurst , Ignatius Loy Britto , Craig Steven Herman , Li Li-Bovet , Michael Thomas Riebe
发明人： Ian C. Ashurst , Ignatius Loy Britto , Craig Steven Herman , Li Li-Bovet , Michael Thomas Riebe
IPC分类号： A61K912
CPC分类号： B65D83/54 , A61M15/009 , A61M2205/0222 , A61M2205/0233
摘要： A metered dose inhaler having part or all of its internal metallic surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising salmeterol, or a salt thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents and one or more excipients.
摘要翻译： 计量剂量吸入器，其部分或全部内部金属表面涂覆有一种或多种氟碳聚合物，任选与一种或多种非碳氟聚合物组合，用于分配包含沙美特罗或其盐的吸入药物制剂，以及碳氟化合物 推进剂，任选地与一种或多种其它药理学活性剂和一种或多种赋形剂组合。
-
公开(公告)号：US06511653B1
公开(公告)日：2003-01-28
申请号：US09506838
申请日：2000-02-18
申请人： Ignatius Loy Britto , Ian Car Ashurst , Craig Steven Herman , Li Li-Bovet , Michael Thomas Riebe
发明人： Ignatius Loy Britto , Ian Car Ashurst , Craig Steven Herman , Li Li-Bovet , Michael Thomas Riebe
IPC分类号： A61K912
CPC分类号： A61K9/008 , A61K31/573 , A61M15/009 , A61M2205/0222 , B65D83/54 , B65D83/752
摘要： A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.
摘要翻译： 一种计量吸入器，其部分或全部内表面涂覆有一种或多种氟碳聚合物，任选与一种或多种非氟碳聚合物组合，用于分配包含二丙酸倍氯米松或其生理上可接受的溶剂合物的吸入药物制剂，以及 氟烃推进剂，任选与一种或多种其它药理学活性剂或一种或多种赋形剂组合。
-
8.发明申请Metered dose inhaler having internal surfaces coated with fluorocarbon polymer 审中-公开计量吸入器内表面涂有氟碳聚合物公开(公告)号：US20050002869A1
公开(公告)日：2005-01-06
申请号：US10895367
申请日：2004-07-21
申请人： Ian Ashurst , Craig Herman , Li Li-Bovet , Michael Riebe
发明人： Ian Ashurst , Craig Herman , Li Li-Bovet , Michael Riebe
CPC分类号： A61K9/008 , A61M15/009
摘要： A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.
摘要翻译： 一种计量吸入器，其部分或全部内表面涂覆有一种或多种氟碳聚合物，任选与一种或多种非氟碳聚合物组合，用于分配包含二丙酸倍氯米松或其生理上可接受的溶剂合物的吸入药物制剂，以及 氟烃推进剂，任选与一种或多种其它药理学活性剂或一种或多种赋形剂组合。
-
公开(公告)号：US06656453B2
公开(公告)日：2003-12-02
申请号：US10185193
申请日：2002-06-27
IPC分类号： A61K912
摘要： This invention relates to aerosol formulations of use for the administration of medicaments by inhalation. More particularly, the invention relates to a pharmaceutical aerosol formulation which comprises particulate salbutamol sulphate having a crystalline form in which the outer layer of the crystals is substantially non-amorphous; and 1,1,1,2-tetrafluoroethane. A method of treating respiratory disorders which comprises administration by inhalation of an effective amount of a pharmaceutical aerosol formulation as defined is also described.
-
公开(公告)号：US06511652B1
公开(公告)日：2003-01-28
申请号：US09506834
申请日：2000-02-18
申请人： Ian C. Ashurst , Ignatius Loy Britto , Craig Steven Herman , Li Li-Bovet , Michael Thomas Riebe
发明人： Ian C. Ashurst , Ignatius Loy Britto , Craig Steven Herman , Li Li-Bovet , Michael Thomas Riebe
IPC分类号： A61K912
CPC分类号： A61K9/008 , A61K31/573 , A61M15/009 , A61M2205/0222 , B65D83/54 , B65D83/752
摘要： A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.
摘要翻译： 一种计量吸入器，其部分或全部内表面涂覆有一种或多种氟碳聚合物，任选与一种或多种非氟碳聚合物组合，用于分配包含二丙酸倍氯米松或其生理上可接受的溶剂合物的吸入药物制剂，以及 氟烃推进剂，任选与一种或多种其它药理学活性剂或一种或多种赋形剂组合。
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.016 秒)
