公开(公告)号：US20160095306A1

公开(公告)日：2016-04-07

申请号：US14965522

申请日：2015-12-10

Applicant: LIFELINE SCIENTIFIC, INC.

Inventor： Christopher P. STEINMAN ,  Jason A. BELTON ,  Kirk C. PALMERTON ,  Karl H. BEITZEL ,  Rick W. WALKER ,  David PETTINATO ,  Matthew COPITHORNE ,  Brian OTTS ,  James V. GUARRERA

IPC: A01N1/02

CPC classification number: A01N1/021 ,  A01N1/0247 ,  A61B17/122 ,  A61B2017/0046 ,  A61B2017/00969 ,  A61B2017/2808 ,  A61M39/0208

Abstract: A method of cannulating vasculature includes inserting the vasculature through a first clamping surface of a cannula and rotating a second clamping surface of the cannula around the first clamping surface to move from an open position towards a closed position. Additionally, the method includes securing the vasculature between the first clamping surface and the second clamping surface.

Abstract translation: 插管脉管系统的方法包括将脉管系统插入穿过套管的第一夹紧表面并且旋转插管的第二夹紧表面围绕第一夹紧表面以从打开位置移动到关闭位置。 另外，该方法包括将脉管系统固定在第一夹紧表面和第二夹紧表面之间。

公开(公告)号：US20210076668A1

公开(公告)日：2021-03-18

申请号：US17015443

申请日：2020-09-09

Applicant: LIFELINE SCIENTIFIC, INC.

Inventor： Peter DE MUYLDER ,  David KRAVITZ ,  Christopher P. STEINMAN ,  David PETTINATO ,  Bernard THEUNIS

IPC: A01N1/02

Abstract: An organ container, which is for storing an organ or tissue and is able to be inserted into an apparatus for at least one of perfusion and transport of the organ or tissue, includes a basin configured to hold the organ or tissue and a perfusate bath. The organ container also includes tubing that (i) is connectable to a source of oxygen, (ii) includes a plurality of holes by which the oxygen may exit the tubing, and (iii) is located within the basin so as to be submerged within the perfusate bath present during the perfusion or transport of the organ or tissue.

公开(公告)号：US20160088834A1

公开(公告)日：2016-03-31

申请号：US14964868

申请日：2015-12-10

Applicant: LIFELINE SCIENTIFIC, INC.

Inventor： Christopher P. STEINMAN ,  David KRAVITZ ,  Aaron R. FERBER ,  Ross LOCKWOOD ,  Rodney H. MONSON ,  Evan D. SHAPIRO

IPC: A01N1/02

CPC classification number: A01N1/0247

Abstract: An apparatus for perfusing an organ or tissue includes a perfusion circuit for perfusing the organ or tissue; an oxygenator for oxygenating perfusate that circulates through the perfusion circuit; and an oxygen supply device such as an oxygen concentrator or an oxygen generator configured to supply oxygen to the oxygenator. A method of perfusing an organ or tissue includes producing oxygen from a device such as an oxygen concentrator and an oxygen generator; supplying the produced oxygen, preferably as the oxygen is produced, to a perfusate to oxygenate the perfusate; and perfusing the organ or tissue with the oxygenated perfusate. The produced oxygen preferably has a concentration greater than the oxygen concentration in air.

Abstract translation: 用于灌注器官或组织的装置包括用于灌注器官或组织的灌注回路; 用于氧化灌注液的氧合器，其通过灌注回路循环; 以及氧气供应装置，例如氧气浓缩器或氧气发生器，其被配置为向氧合器供应氧气。 灌注器官或组织的方法包括从诸如氧气浓缩器和氧气发生器的装置产生氧气; 将产生的氧优选作为产生氧气供应给灌注液以使灌注液充氧; 并用含氧灌注液灌注器官或组织。 所产生的氧优选具有大于空气中的氧浓度的浓度。

公开(公告)号：US20160295857A1

公开(公告)日：2016-10-13

申请号：US15190360

申请日：2016-06-23

Applicant: LIFELINE SCIENTIFIC, INC.

Inventor： David KRAVITZ ,  Christopher P. STEINMAN ,  David PETTINATO ,  Matthew COPITHORNE ,  Brian OTTS ,  Robert J. ALLEN ,  Frank P. NANNA ,  Peter DEMUYLDER

IPC: A01N1/02

CPC classification number: A01N1/0252 ,  A01N1/0247 ,  A01N1/0273

Abstract: An apparatus for at least one of storage, treatment, assessment and transport of an organ or tissue includes a cooling container configured to cool the organ or tissue, a perfusion circuit configured to perfuse the organ or tissue, and a sample compartment for holding a biological sample. Preferred apparatus has a first internal compartment under a first cover (lid) of the apparatus that includes the coolant container and the sample compartment. The apparatus can include a second internal compartment under a second cover (lid) of the apparatus, the second internal compartment including at least part of the perfusion circuit and a sample compartment.

公开(公告)号：US20200288701A1

公开(公告)日：2020-09-17

申请号：US16353188

申请日：2019-03-14

Applicant: LIFELINE SCIENTIFIC, INC.

Inventor： David PETTINATO ,  Christopher P. STEINMAN ,  Alan K. WU

IPC: A01N1/02

Abstract: Disclosed is an oxygenator device for oxygenating a perfusate solution to be perfused through an organ or tissue. The device includes an inlet configured to receive oxygen from an oxygen supply; and tubing connected to the inlet, the tubing including a plurality of holes by which the received oxygen may exit the tubing.

公开(公告)号：US20150366183A1

公开(公告)日：2015-12-24

申请号：US14840392

申请日：2015-08-31

Applicant: LIFELINE SCIENTIFIC, INC.

Inventor： Christopher P. STEINMAN ,  John STARK ,  Joel C. HAGEN ,  Aaron R. FERBER ,  Rodney H. MONSON ,  Evan D. SHAPIRO

IPC: A01N1/02

CPC classification number: A01N1/0247 ,  A01N1/0273

Abstract: A method of perfusing an organ or tissue includes perfusing the organ or tissue with a perfusion apparatus; detecting a condition representing at least one of an attitude of the perfusion apparatus or at least one shock experienced by the perfusion apparatus; and altering perfusion based upon the detected condition and/or recording the detected condition.

Abstract translation: 灌注器官或组织的方法包括用灌注装置灌注器官或组织; 检测表示所述灌注装置的姿势或所述灌注装置所经受的至少一次震动中的至少一个的状况; 以及基于检测到的条件改变灌注和/或记录检测到的状况。

公开(公告)号：US20150272111A1

公开(公告)日：2015-10-01

申请号：US14739800

申请日：2015-06-15

Applicant: LIFELINE SCIENTIFIC, INC.

Inventor： Christopher P. STEINMAN ,  Jeffrey S. LOUIS

IPC: A01N1/02

CPC classification number: A01N1/0247

Abstract: A filter for filtering perfusate is integrated with an exterior portion of an organ container. The filter may be used in an apparatus for perfusing an organ. The perfusion apparatus may include an organ container configured to contain an organ, the filter integrated with an exterior portion of the organ container, and another filter. At least the filter integrated with an exterior portion of the organ container may be provided in a sterilized disposable kit.

Abstract translation: 用于过滤灌洗液的过滤器与器官容器的外部部分结合。 过滤器可用于灌注器官的装置中。 灌注装置可以包括构造成容纳器官的器官容器，与器官容器的外部整合的过滤器和另一过滤器。 至少与器官容器的外部整合的过滤器可以设置在灭菌的一次性套件中。

公开(公告)号：US20140329220A1

公开(公告)日：2014-11-06

申请号：US14335393

申请日：2014-07-18

Applicant: LIFELINE SCIENTIFIC, INC.

Inventor： Christopher P. STEINMAN ,  Jason A. BELTON ,  Kirk C. PALMERTON ,  Karl H. BEITZEL ,  Rick W. WALKER ,  Matthew COPITHORNE ,  Brian OTTS ,  James V. GUARRERA

IPC: A01N1/02 ,  A61B17/28

CPC classification number: A01N1/0247 ,  A61B17/122 ,  A61B17/28 ,  A61B2017/00907 ,  A61B2017/00969 ,  A61B2017/2808

Abstract: A cannula has a longitudinal base member having a first clamping end and a longitudinal arm member pivotally attached to the longitudinal base member and having a second clamping end, the cannula being in a closed position when the first and second clamping ends are brought together. A first clamp member is located at the first clamping end and has a first passage. A second clamp member is rotatably attached to the aim member at the second clamping end and has a second passage. The first and second passages form a combined passage when the clamp is in the closed position. The cannula may have a first locking member positioned on the arm member and a second locking member positioned on the base member. The first and second locking members interact with each other to lock the cannula in the closed position.

Abstract translation: 套管具有纵向底座构件，该纵向底座构件具有第一夹紧端和纵向臂构件，所述纵向臂构件可枢转地附接到纵向底座构件并且具有第二夹紧端，当第一和第二夹紧端部接合在一起时，套管处于关闭位置。 第一夹紧构件位于第一夹紧端并且具有第一通道。 第二夹紧构件在第二夹持端处可旋转地附接到瞄准构件，并且具有第二通道。 当夹具处于关闭位置时，第一和第二通道形成组合的通道。 套管可以具有定位在臂构件上的第一锁定构件和定位在基座构件上的第二锁定构件。 第一和第二锁定构件相互作用以将套管锁定在关闭位置。