专利检索 ap:("LES LABORATOIRES SERVIER" OR "VERNALIS (R&D) LTD") AND inv:"Michael BURBRIDGE" 第 1 页

1.

发明申请
PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开

公开(公告)号：US20180273538A1

公开(公告)日：2018-09-27

申请号：US15763626

申请日：2016-09-30

申请人： LES LABORATOIRES SERVIER , VERNALIS (R&D) LTD

发明人： Andrea FIUMANA , Nicolas FOLOPPE , Stuart RAY , David WALMSLEY , András KOTSCHY , Michael BURBRIDGE , Francisco Humberto CRUZALEGUI

IPC分类号： C07D487/04 , A61P35/00 , A61K31/519 , A61K45/06 , A61K31/5377 , C07D519/00 , C07D471/04 , A61K31/437 , A61K31/444

CPC分类号： C07D487/04 , A61K31/437 , A61K31/444 , A61K31/519 , A61K31/5377 , A61K45/06 , A61P35/00 , C07D471/04 , C07D519/00

摘要： Compounds of formula (I): wherein R1, R2, W3, W4, A1, and A2 are as defined in the description.Medicinal products containing the same which are useful in treating cancer, neurodegenerative disorders and metabolic disorders.

2.

发明申请
IMIDAZO[4,5-b]PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开

公开(公告)号：US20180273528A1

公开(公告)日：2018-09-27

申请号：US15763248

申请日：2016-09-30

申请人： LES LABORATOIRES SERVIER , VERNALIS (R&D) LTD

发明人： Balázs BÁLINT , András KOTSCHY , Melinda SIPOS , Csaba WÉBER , Nicolas FOLOPPE , David WALMSLEY , Michael BURBRIDGE , Francisco Humberto CRUZALEGUI

IPC分类号： C07D471/04 , A61K31/444 , A61K45/06 , A61P35/00

CPC分类号： C07D471/04 , A61K31/444 , A61K45/06 , A61P35/00

摘要： Compounds of formula (I): wherein R1, R2, R3, R4, and R5 are as defined in the description.Medicinal products containing the same which are useful in treating cancer, neurodegenerative disorders and metabolic disorders.

3.

发明申请
COMBINATION BETWEEN TRIFLURIDINE/TIPIRACIL HYDROCHLORIDE, AN ANTITUMOR PLATINIUM COMPLEX, AND AN IMMUNE CHECKPOINT MODULATOR 审中-公开

公开(公告)号：US20200009104A1

公开(公告)日：2020-01-09

申请号：US16490656

申请日：2018-03-16

申请人： LES LABORATOIRES SERVIER

发明人： Jean-Pierre ABASTADO , Nadia AMELLAL , Alain BRUNO , Michael BURBRIDGE , Valérie CATTAN , Catherine LEGER

IPC分类号： A61K31/282 , C07K16/28 , A61K31/7072 , A61K31/513 , A61K9/00 , A61P35/00

摘要： A combination comprising:an FTD-TPI drug,an anti-tumor platinum complex,and an immune checkpoint modulator. Medicinal products containing the same which are useful in treating cancer.

4.

发明申请
ASSOCIATION BETWEEN 3-[(3--2-OXO-2,3-DIHYDRO-1H-INDOL-5-YL)METHYL]-1,3-THIAZOLIDINE-2,4-DIONE AND AN EGFR TYR KINASE INHIBITOR 审中-公开
标题翻译： 3 - [（3-二氧代-2,3-二氢-1H-吲哚-5-基）甲基] -1,3-噻唑烷-2,4-二酮和EGFR TYR激酶抑制剂之间的结合

公开(公告)号：US20170027952A1

公开(公告)日：2017-02-02

申请号：US15219691

申请日：2016-07-26

申请人： LES LABORATOIRES SERVIER

发明人： Michael BURBRIDGE , Valérie CATTAN , Anne JACQUET-BESCOND

IPC分类号： A61K31/5377 , A61K31/517

摘要： Association between 3-[(3-{[4-(4-morpholinylmethyl)-1H-pyrrol-2-yl]methylene}-2-oxo-2,3-dihydro-1H-indol-5-yl)methyl]-1,3-thiazolidine-2,4-dione of formula (I): or a Z or E isomer thereof and/or an addition salt thereof with a pharmaceutically acceptable acid or base, and a human epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor.Medicinal products containing the same which are useful in treating non-small cell lung cancer.

摘要翻译： 含有该药物的药物可用于治疗非小细胞肺癌。