公开(公告)号：US20150018533A1

公开(公告)日：2015-01-15

申请号：US14322864

申请日：2014-07-02

Applicant: Korea Advanced Institute of Science and Technology

Inventor： Hak-Sung Kim ,  Woosung Heu ,  Joong-Jae Lee ,  Seong-Min Jo

IPC: C07K14/195

CPC classification number: C07K14/195 ,  C07K14/705 ,  C07K16/065 ,  C07K2319/70

Abstract: The present invention relates to a polypeptide (repebody) selectively bound to an immunoglobulin G, a polynucleotide which encodes the repebody, a vector containing the polynucleotide, a recombinant microorganism in which the polynucleotide is introduced, a method for producing the repebody using the recombinant microorganism, and a method for immobilizing or purifying an immunoglobulin G using the repebody. The repebody according to the present invention is useful as utilized for immobilization of an immunoglobulin G, purification of an immunoglobulin G, and production of an immunosensor, since the repebody selectively bound to an immunoglobulin G.

Abstract translation: 本发明涉及选择性结合免疫球蛋白G的多肽（重组体），编码重组体的多核苷酸，含有多核苷酸的载体，引入多核苷酸的重组微生物，使用重组微生物产生重组体的方法 ，以及使用该重复体固定或纯化免疫球蛋白G的方法。 根据本发明的重组体可用于固定免疫球蛋白G，免疫球蛋白G的纯化和免疫传感器的产生，因为选择性结合免疫球蛋白G的重组体。

公开(公告)号：US09777046B2

公开(公告)日：2017-10-03

申请号：US14322864

申请日：2014-07-02

Applicant: Korea Advanced Institute of Science and Technology

Inventor： Hak-Sung Kim ,  Woosung Heu ,  Joong-Jae Lee ,  Seong-Min Jo

IPC: C07K14/195 ,  C07K14/705 ,  C07K16/06

CPC classification number: C07K14/195 ,  C07K14/705 ,  C07K16/065 ,  C07K2319/70

Abstract: The present invention relates to a polypeptide (repebody) selectively bound to an immunoglobulin G, a polynucleotide which encodes the repebody, a vector containing the polynucleotide, a recombinant microorganism in which the polynucleotide is introduced, a method for producing the repebody using the recombinant microorganism, and a method for immobilizing or purifying an immunoglobulin G using the repebody. The repebody according to the present invention is useful as utilized for immobilization of an immunoglobulin G, purification of an immunoglobulin G, and production of an immunosensor, since the repebody selectively bound to an immunoglobulin G.