公开(公告)号：US20170252319A1

公开(公告)日：2017-09-07

申请号：US15449011

申请日：2017-03-03

Applicant: Korea Advanced Institute of Science and Technology

Inventor： Haeshin Lee ,  WhuiSu Shim ,  Mihyun Lee ,  Joseph Paul Park

IPC: A61K31/353 ,  A61K47/10

CPC classification number: A61K31/353 ,  A61K9/08 ,  A61K9/146 ,  A61K47/10

Abstract: The present invention relates to a flavonoid-poly(ethylene glycol) complex comprising flavonoid compounds and poly(ethylene glycol) and a preparation method of the same. The flavonoid-poly(ethylene glycol) complex of the invention displays a significantly improved solubility of flavonoid which is usually insoluble in an aqueous solution and contains flavonoid compounds distributed evenly in the complex so that the complex of the invention can be effectively used for the establishment of a method for enhancing solubility of flavonoid in an aqueous solution and a method for enhancing bioavailability of flavonoid.