公开(公告)号：US20240366652A1

公开(公告)日：2024-11-07

申请号：US18689008

申请日：2022-09-02

Applicant: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION

Inventor： Yasuharu NAKASHIMA ,  Yukio AKASAKI ,  Takuya SUEISHI ,  Masakazu TOYA ,  Masanari KUWAHARA ,  Taisuke UCHIDA ,  Tomoaki TSUTSUI ,  Hidetoshi TSUSHIMA

IPC: A61K31/728 ,  A61K31/436 ,  A61P19/02

Abstract: An osteoarthritis progression inhibitor contains, as active substances, a G protein-coupled receptor kinase 5 inhibitor, and hyaluronic acid or a pharmaceutically acceptable salt thereof. The G protein-coupled receptor kinase 5 inhibitor may be Amlexanox. The osteoarthritis progression inhibitor may be administered by intraarticular injection. An osteoarthritis progression inhibition kit contains a G protein-coupled receptor kinase 5 inhibitor, and hyaluronic acid or a pharmaceutically acceptable salt thereof.