公开(公告)号：US20240050598A1

公开(公告)日：2024-02-15

申请号：US18475470

申请日：2023-09-27

Applicant: Jubilant Draximage inc.

Inventor： Umamaheshwar M. Prasad ,  Harmik Sohi ,  Rahul Hasija ,  Dinesh Kumar ,  Kamal S. Mehta ,  Raj Vijaya Kuniyil Kulangara ,  Ashutosh Agarwal ,  Dharam Vir

IPC: A61K51/04 ,  A61K9/19 ,  A61K31/66 ,  A61K51/02

CPC classification number: A61K51/0478 ,  A61K9/19 ,  A61K31/66 ,  A61K51/025

Abstract: The present invention relates to a stable pharmaceutical composition of tetrofosmin or pharmaceutically acceptable salts thereof. It also relates to a lyophilized non-radioactive kit which upon reconstitution with 99mTc-pertechnetate solution gives a stable 99mTc-tetrofosmin radiopharmaceutical composition. It also provides process for the preparation of said radiopharmaceutical compositions and their use in diagnostic imaging procedures. The compositions provide desirable technical attributes such as stability, high radiochemical purity (RCP) and desired bio-distribution.