专利检索 ap:("John Kink" OR "Katherine Worledge" OR "Douglas Stafford") AND inv:"Katherine Worledge" 第 1 页

1.

发明申请
Antibodies to cytokines in the prevention and treatment of inflammatory bowel disease 失效
标题翻译：抗细胞因子在预防和治疗炎性肠病中的应用

公开(公告)号：US20050053604A1

公开(公告)日：2005-03-10

申请号：US10627499

申请日：2003-07-25

申请人： John Kink , Katherine Worledge , Douglas Stafford

发明人： John Kink , Katherine Worledge , Douglas Stafford

IPC分类号： A61K38/00 , A61K39/395 , A61P29/00 , C07K16/00 , C07K16/24

CPC分类号： C07K16/248 , A61K38/00 , C07K16/241 , C07K16/244 , C07K2317/11 , C07K2317/23 , Y10S424/81 , Y10S530/853 , Y10S530/861

摘要： Methods are described for treating inflammatory bowel disease in animals, including humans. Specific avian polyclonal antibodies directed to proinflammatory cytokines (such as IL-6 and TNF) are shown to have a beneficial effect in animal models predictive of human therapy for the treatment of colitis, including Crohn's disease.

摘要翻译： 描述了用于治疗动物（包括人）中的炎症性肠病的方法。针对促炎细胞因子（如IL-6和TNF）的特异性禽多克隆抗体显示在预测人类治疗结肠炎包括克罗恩病的人类模型的动物模型中具有有益效果。