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公开(公告)号:US08492357B2
公开(公告)日:2013-07-23
申请号:US13057146
申请日:2009-07-24
申请人: Jesper Worm , Jan Stenvang , Susanna Obad , Sakari Kauppinen
发明人: Jesper Worm , Jan Stenvang , Susanna Obad , Sakari Kauppinen
IPC分类号: A61K48/00
CPC分类号: C12N15/113 , C12N2310/141 , C12N2310/3231
摘要: The present invention relates to the modulation of immunoregulatory proteins, including cytokines, such as colony stimulatory factors (CSF) via the use of microRNA-155 modulators.
摘要翻译: 本发明涉及通过使用微小RNA-155调节剂调节免疫调节蛋白,包括细胞因子,例如集落刺激因子(CSF)。
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公开(公告)号:US20120115924A1
公开(公告)日:2012-05-10
申请号:US13057146
申请日:2009-07-24
申请人: Jesper Worm , Jan Stenvang , Susanna Obad , Sakari Kauppinen
发明人: Jesper Worm , Jan Stenvang , Susanna Obad , Sakari Kauppinen
IPC分类号: A61K31/7088 , C12N5/0787 , C12N5/0786 , C12N5/071 , C12N5/0789
CPC分类号: C12N15/113 , C12N2310/141 , C12N2310/3231
摘要: The present invention relates to the modulation of immunoregulatory proteins, including cytokines, such as colony stimulatory factors (CSF) via the use of microRNA-155 modulators.
摘要翻译: 本发明涉及通过使用微小RNA-155调节剂调节免疫调节蛋白,包括细胞因子,例如集落刺激因子(CSF)。
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3.
公开(公告)号:US20140194491A1
公开(公告)日:2014-07-10
申请号:US14128792
申请日:2012-06-11
申请人: Moustapha Kassem , Basem Abdallah , Hanna Taipaleenmaeki , Sakari Kauppinen , Tilde Eskildsen , Jan Stenvang
发明人: Moustapha Kassem , Basem Abdallah , Hanna Taipaleenmaeki , Sakari Kauppinen , Tilde Eskildsen , Jan Stenvang
IPC分类号: C12N15/113
CPC分类号: C12N15/113 , A61K31/7088 , C12N2310/113
摘要: There is provided nucleic acids (mir-138 Antimirs) for use in treating or preventing bone loss in a patient. Also there is provided a method for reducing the levels of endogenous mir-138 in a cell.
摘要翻译: 提供用于治疗或预防患者骨质流失的核酸(mir-138 Antimirs)。 还提供了一种降低细胞内源性mir-138水平的方法。
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