公开(公告)号：US20210155711A1

公开(公告)日：2021-05-27

申请号：US17150269

申请日：2021-01-15

Applicant: Janssen Biotech, Inc.

Inventor： Stephen McCarthy ,  Bernard Scallon ,  William Strohl ,  Susan Tam ,  Omid Vafa

IPC: C07K16/32 ,  C07K16/00 ,  C07K16/28

Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.

公开(公告)号：US10053513B2

公开(公告)日：2018-08-21

申请号：US14818864

申请日：2015-08-05

Applicant: Janssen Biotech, Inc.

Inventor： Stephen McCarthy ,  Bernard Scallon ,  Susan Tam ,  William Strohl ,  Omid Vafa

IPC: C07K16/32 ,  C07K16/00 ,  C07K16/28 ,  A61K39/00

CPC classification number: C07K16/32 ,  A61K2039/505 ,  C07K16/00 ,  C07K16/2887 ,  C07K2317/52 ,  C07K2317/524 ,  C07K2317/54 ,  C07K2317/70 ,  C07K2317/71 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/75 ,  C07K2317/92

Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.

公开(公告)号：US20150337053A1

公开(公告)日：2015-11-26

申请号：US14818864

申请日：2015-08-05

Applicant: Janssen Biotech, Inc.

Inventor： Stephen McCarthy ,  Bernard Scallon ,  Susan Tam ,  William Strohl ,  Omid Vafa

IPC: C07K16/32 ,  C07K16/28

CPC classification number: C07K16/32 ,  A61K2039/505 ,  C07K16/00 ,  C07K16/2887 ,  C07K2317/52 ,  C07K2317/524 ,  C07K2317/54 ,  C07K2317/70 ,  C07K2317/71 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/75 ,  C07K2317/92

Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.

Abstract translation: 抗体和其他具有Fc区变化的含Fc分子，其与Fcγ受体的结合降低并导致活性，并可用于治疗各种疾病和病症。