公开(公告)号：US20200148736A1

公开(公告)日：2020-05-14

申请号：US16746052

申请日：2020-01-17

Applicant: Janssen Biotech, Inc.

Inventor： Thomas Rutkoski ,  Alexey Teplyakov ,  Nicole Wunderler

IPC: C07K14/535 ,  A61K45/06 ,  A61K38/19

Abstract: GM-CSF variants, polynucleotides encoding them, and methods of making and using the foregoing are useful in treatment of immune-related disorders, such as inflammatory bowel disease (IBD).

公开(公告)号：US11208450B2

公开(公告)日：2021-12-28

申请号：US16746052

申请日：2020-01-17

Applicant: Janssen Biotech, Inc.

Inventor： Thomas Rutkoski ,  Alexey Teplyakov ,  Nicole Wunderler

IPC: C07K14/535 ,  A61K38/19 ,  C12N15/00 ,  C12N5/00 ,  A61K45/06

Abstract: GM-CSF variants, polynucleotides encoding them, and methods of making and using the foregoing are useful in treatment of immune-related disorders, such as inflammatory bowel disease (IBD).

公开(公告)号：US10562948B2

公开(公告)日：2020-02-18

申请号：US15616216

申请日：2017-06-07

Applicant: Janssen Biotech, Inc.

Inventor： Thomas Rutkoski ,  Alexey Teplyakov ,  Nicole Wunderler

IPC: C07K14/535 ,  A61K38/19 ,  A61K45/06

Abstract: GM-CSF variants, polynucleotides encoding them, and methods of making and using the foregoing are useful in treatment of immune-related disorders, such as inflammatory bowel disease (IBD).

公开(公告)号：US20170355742A1

公开(公告)日：2017-12-14

申请号：US15616216

申请日：2017-06-07

Applicant: Janssen Biotech, Inc.

Inventor： Thomas Rutkoski ,  Alexey Teplyakov ,  Nicole Wunderler

IPC: C07K14/535 ,  A61K45/06 ,  A61K38/19

Abstract: GM-CSF variants, polynucleotides encoding them, and methods of making and using the foregoing are useful in treatment of immune-related disorders, such as inflammatory bowel disease (IBD).