公开(公告)号：US20230094867A1

公开(公告)日：2023-03-30

申请号：US17825244

申请日：2022-05-26

Applicant: Janssen Biotech, Inc.

Inventor： Katharine D. Grugan ,  Christian R. Martinez ,  Nan Wei ,  Hong Mimi Zhou

IPC: C07K16/42 ,  G01N33/68

Abstract: In certain aspects, the disclosure relates to anti-idiotype antibodies and antigen-binding portions thereof that specifically bind a CD9B441 containing protein, e.g., an antibody or antigen-binding portions thereof. In some aspects, the anti-idiotype antibodies and antigen-binding portions of the present disclosure can be used in methods to detect and quantify cells expressing chimeric antigen receptors that include CD9B441.