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公开(公告)号：US12091406B2
公开(公告)日：2024-09-17
申请号：US18507566
申请日：2023-11-13
发明人： Xin Cheng , Luoheng Qin , Feng Ren
IPC分类号： C07D413/14 , C07D413/06 , C07D413/12 , C07D417/06 , C07D417/12 , C07D417/14 , C07D498/04
CPC分类号： C07D413/14 , C07D413/06 , C07D413/12 , C07D417/06 , C07D417/12 , C07D417/14 , C07D498/04
摘要： Described herein are KAT6A inhibitors of Formula (Ia) and pharmaceutical compositions comprising said inhibitors. The subject compounds of Formula (Ia) and compositions are useful for the treatment of a disease or disorder associated with KAT6A
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公开(公告)号：US12077538B2
公开(公告)日：2024-09-03
申请号：US18507595
申请日：2023-11-13
发明人： Hongfu Lu , Huaxing Yu , Xiao Ding , Feng Ren
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： Described herein are DGKalpha inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with DGKalpha.
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公开(公告)号：US12071443B2
公开(公告)日：2024-08-27
申请号：US18339362
申请日：2023-06-22
IPC分类号： C07D471/04 , C07D519/00
CPC分类号： C07D519/00 , C07D471/04
摘要： Described herein are PHD inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of inflammatory bowel disease.
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公开(公告)号：US11780854B2
公开(公告)日：2023-10-10
申请号：US18110261
申请日：2023-02-15
IPC分类号： C07D519/00 , C07D471/04
CPC分类号： C07D519/00 , C07D471/04
摘要： Described herein are PHD inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of anemia.
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公开(公告)号：US12103915B2
公开(公告)日：2024-10-01
申请号：US18529689
申请日：2023-12-05
发明人： Xiao Ding , Jinxin Liu , Feng Ren , Jianfei Wan , Wei Zhu
IPC分类号： C07D231/56 , A61P35/00 , C07D209/44 , C07D215/14 , C07D401/04 , C07D403/08 , C07D471/04 , C07D487/04
CPC分类号： C07D231/56 , A61P35/00 , C07D209/44 , C07D215/14 , C07D401/04 , C07D403/08 , C07D471/04 , C07D487/04
摘要： The disclosure provides for compounds and methods for modulating or inhibiting TEAD. Further provided herein are pharmaceutical compositions comprising the TEAD inhibitors and methods of treatment using the TEAD inhibitors or the pharmaceutical compositions.
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公开(公告)号：US11731987B2
公开(公告)日：2023-08-22
申请号：US18110259
申请日：2023-02-15
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： Described herein are PHD inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of inflammatory bowel disease.
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公开(公告)号：US11731944B2
公开(公告)日：2023-08-22
申请号：US18107127
申请日：2023-02-08
发明人： Xiao Ding , Jingjing Peng , Feng Ren , Xiaoyu Ding , Bogdan Zagribelnyy , Yan A. Ivanenkov
IPC分类号： C07D233/96 , A61P31/14
CPC分类号： C07D233/96 , A61P31/14
摘要： Provided herein are compounds, pharmaceutical compositions, and methods for treating a SARS-CoV-2 infection.
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公开(公告)号：US11999713B2
公开(公告)日：2024-06-04
申请号：US18509658
申请日：2023-11-15
发明人： Chiachun Chen , Xiao Ding , Xiaosong Liu , Feng Ren , Hailong Wang
IPC分类号： C07D401/04 , C07D239/95 , C07D403/04 , C07D471/04 , C07D487/04
CPC分类号： C07D401/04 , C07D239/95 , C07D403/04 , C07D471/04 , C07D487/04
摘要： Described herein are MAT2A inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of a disease or disorder associated with MAT2A.
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