专利检索 ap:("Inozyme Pharma, Inc.") AND inv:"Deborah Wenkert" 第 1 页

1.

发明公开
Treatment of ENPP1 Deficiency and ABCC6 Deficiency 审中-公开

公开(公告)号：US20240181021A1

公开(公告)日：2024-06-06

申请号：US18319821

申请日：2023-05-18

申请人： Inozyme Pharma, Inc.

发明人： Pedro Huertas , Deborah Wenkert

IPC分类号： A61K38/46 , A61P19/08 , C12N9/16

CPC分类号： A61K38/465 , A61P19/08 , C12N9/16 , C12Y301/04001 , C07K2319/30

摘要： The present disclosure provides, among other things, specific doses of an ENPP1 agent for in vivo treatment of an ENPP1 deficiency, such as for treatment of Generalized Arterial Calcification of Infancy (GACI), Autosomal Recessive Hypophosphatemic Rickets 2 (ARHR2), and other diseases resulting from pathological calcification, ENPP1 deficiency, ABCC6 deficiency such as diseases or disorders involving ectopic calcification of soft tissue in a subject.