公开(公告)号：US20230114765A1

公开(公告)日：2023-04-13

申请号：US17812310

申请日：2022-07-13

申请人： Incyte Corporation

发明人： Zhenwu Li ,  Zhiyong YU ,  Jeremy Roach ,  Gia Hoang ,  Bin HU ,  Gencheng Li ,  Rory McAtee ,  Ken Mukai ,  Rocco Policarpo ,  Robert Susick ,  Xiaozhao Wang ,  Wenqing Yao

IPC分类号： C07D471/04 ,  C07D519/00

摘要： Disclosed are compounds of Formula I, methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.