METHOD FOR GENERATING TRANSCRANIAL MAGNETIC STIMULATION (TMS) COIL POSE ATLAS BASED ON ELECTROMAGNETIC SIMULATING CALCULATION

    公开(公告)号:US20220218220A1

    公开(公告)日:2022-07-14

    申请号:US17539150

    申请日:2021-11-30

    Abstract: A method for generating a transcranial magnetic stimulation (TMS) coil pose atlas based on electromagnetic simulating calculation includes: constructing coil array positions and orientations of a scalp in a standard Montreal Neurological Institute (MNI) space and matching the coil array positions and orientations of the scalp to a brain space of an individual to obtain coil array positions and orientations of the brain space of the individual; using a finite element calculation method to simulate the coil array positions of the brain space of the individual to obtain induced electric field distributions of brain tissue in different coil orientations; obtaining optimal regulation effects based on the induced electric field distributions of the brain tissue; and obtaining a coil position and orientation corresponding to each optimal regulation effect as an optimal coil pose of each divided brain area of the individual, and constructing a TMS coil pose atlas of the individual.

    NEUROVASCULAR COUPLING ANALYTICAL METHOD BASED ON ELECTROENCEPHALOGRAM AND FUNCTIONAL NEAR-INFRARED SPECTROSCOPY

    公开(公告)号:US20210282694A1

    公开(公告)日:2021-09-16

    申请号:US16961700

    申请日:2016-11-03

    Abstract: A neurovascular coupling analytical method based on an electroencephalogram and functional near-infrared spectroscopy includes: S100: acquiring an electroencephalogram signal and a brain hemodynamic signal; S110: extracting an event-related potential signal from the electroencephalogram signal; S120: extracting a time characteristic from the event-related potential signal; S130: extracting a hemodynamic response function from the brain hemodynamic signal; S140: extracting an amplitude characteristic and time characteristics from the hemodynamic response function; and S150: analyzing influence of the time characteristic of the event-related potential signal on the amplitude characteristic and the time characteristics of the hemodynamic response function to obtain a coupling result. The time characteristic of the event-related potential signal is a delay. The amplitude characteristic of the hemodynamic response function is a peak amplitude, and the time characteristics of the hemodynamic response function comprises a rising delay, a peak time, and a full width at half maximum.

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