公开(公告)号：US11882858B2

公开(公告)日：2024-01-30

申请号：US15752951

申请日：2016-09-20

申请人： INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY

发明人： Kwang Dong Kim ,  Ji Yun Yoo ,  Hyung Won Ryu ,  Soojong Park ,  Kiwon Lee ,  Ki Hun Park ,  Sangseok Oh

IPC分类号： A23L33/105 ,  A61Q19/02 ,  A61K31/352 ,  A61K36/38 ,  A61K8/49 ,  A61K8/9789 ,  A23L29/206 ,  A61K8/9783 ,  A61P17/00 ,  A61K8/02 ,  A61K8/04 ,  A61K8/06

CPC分类号： A23L33/105 ,  A23L29/206 ,  A61K8/022 ,  A61K8/042 ,  A61K8/06 ,  A61K8/498 ,  A61K8/9783 ,  A61K8/9789 ,  A61K31/352 ,  A61K36/38 ,  A61P17/00 ,  A61Q19/02 ,  A61K2121/00 ,  A61K2800/43 ,  A61K2800/805

摘要： A skin whitening composition includes β-mangostin or a cosmetically acceptable salt thereof as an effective ingredient. β-Mangostin represented by Chemical Formula 1 suppresses the expression of tyrosinase and TRP-1 (tyrosinase-related protein-1) and induces autophagy of a melasosome. As such, it was confirmed that the β-mangostin not only suppresses melanin production but also exhibits the effect of removing previously formed melanin. Accordingly, the β-mangostin can be advantageously used as a functional material for skin whitening and skin lightening.