专利检索 ap:("INCYTE CORPORATION") AND inv:"Matthew McCammant" 第 1 页

1.

发明公开
CYCLIC UREA KRAS INHIBITORS 审中-公开

公开(公告)号：US20240358702A1

公开(公告)日：2024-10-31

申请号：US18638034

申请日：2024-04-17

申请人： INCYTE CORPORATION

发明人： Onur ATASOYLU , Peter Carlsen , Bin HU , Chengtsung Lai , Matthew McCammant , Alexander Sokolsky , Xiaozhao Wang

IPC分类号： A61K31/513 , A61P35/00 , C07D239/10

CPC分类号： A61K31/513 , A61P35/00 , C07D239/10

摘要： Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.

2.

发明授权
Quinoline compounds as inhibitors of KRAS 有权

公开(公告)号：US11939328B2

公开(公告)日：2024-03-26

申请号：US18046303

申请日：2022-10-13

申请人： Incyte Corporation

发明人： Qinda Ye , Matthew McCammant , Artem Shvartsbart , Wenyu Zhu , Bin Hu , Chao Qi , Xiaozhao Wang , Wenqing Yao , Alexander Sokolsky

IPC分类号： C07D471/04 , A61P35/00

CPC分类号： C07D471/04 , A61P35/00

摘要： Disclosed are compounds of Formula I, methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.