公开(公告)号：US20140037744A1

公开(公告)日：2014-02-06

申请号：US14054996

申请日：2013-10-16

Applicant: IDCAPS

Inventor： Pierre BUISSON ,  Carine CHAIGNEAU ,  Jean-Eudes VENDEVILLE

IPC: A61K9/50 ,  A61K38/44 ,  A23L2/52 ,  A61K31/375

CPC classification number: A61K31/375 ,  A23D9/00 ,  A23L2/52 ,  A23L29/262 ,  A23L29/275 ,  A23L33/105 ,  A23L33/115 ,  A23L33/15 ,  A23L33/16 ,  A23P10/30 ,  A23P20/18 ,  A61K9/50 ,  A61K9/5036 ,  A61K9/5042 ,  A61K9/5089 ,  A61K38/446 ,  B05D1/22

Abstract: Disclosed is a microcapsule including a core having an oxidizable active (OA), the outer part of said core being in a solid form, and a water insoluble coating obtained from an encapsulating agent (EA), with the coating surrounding said core. In particular, there is disclosed a microcapsule wherein the EA is water soluble or organic solvent, in particular ethanol, soluble, or a microcapsule wherein said EA is an agent, the water solubility of which is pH-dependent. In particular, the core does not consist in or comprise a metal oxide, and the coating does not comprise a disintegrant, in particular sodium starch glycolate. Also disclosed is a process for preparing the microcapsules.

Abstract translation: 公开了一种微胶囊，其包括具有可氧化活性物质（OA）的核心，所述核心的外部部分为固体形式，以及由包封剂（EA）获得的水不溶性涂层，所述涂层包围所述核心。 特别地，公开了一种微胶囊，其中EA是水溶性或有机溶剂，特别是乙醇，可溶性或微胶囊，其中所述EA是水溶性为pH依赖性的试剂。 特别地，芯不包含或包含金属氧化物，并且涂层不包含崩解剂，特别是羟乙酸淀粉钠。 还公开了一种制备微胶囊的方法。

公开(公告)号：US20160184264A1

公开(公告)日：2016-06-30

申请号：US15063534

申请日：2016-03-08

Applicant: IDCAPS

Inventor： Pierre BUISSON ,  Carine CHAIGNEAU ,  Jean-Eudes VENDEVILLE

IPC: A61K31/375 ,  B05D1/22 ,  A61K9/50

CPC classification number: A61K31/375 ,  A23D9/00 ,  A23L2/52 ,  A23L29/262 ,  A23L29/275 ,  A23L33/105 ,  A23L33/115 ,  A23L33/15 ,  A23L33/16 ,  A23P10/30 ,  A23P20/18 ,  A61K9/50 ,  A61K9/5036 ,  A61K9/5042 ,  A61K9/5089 ,  A61K38/446 ,  B05D1/22

Abstract: Disclosed is a microcapsule including a core having an oxidizable active (OA), the outer part of said core being in a solid form, and a water insoluble coating obtained from an encapsulating agent (EA), with the coating surrounding said core. In particular, the EA can be water soluble or organic solvent soluble, in particular in ethanol. The microcapsule can also include an EA in which the water solubility is pH-dependent. Also, the core does not contain a metal oxide, and the coating does not include a disintegrant, such as sodium starch glycolate. Also disclosed is a process for preparing the microcapsules.

Abstract translation: 公开了一种微胶囊，其包括具有可氧化活性物质（OA）的核心，所述核心的外部部分为固体形式，以及由包封剂（EA）获得的水不溶性涂层，所述涂层包围所述核心。 特别地，EA可以是水溶性或有机溶剂可溶的，特别是在乙醇中。 微胶囊还可以包括其中水溶性依赖于pH的EA。 此外，芯不含有金属氧化物，并且涂层不包括崩解剂，例如淀粉羟乙酸钠。 还公开了一种制备微胶囊的方法。

公开(公告)号：US20190022058A1

公开(公告)日：2019-01-24

申请号：US16141128

申请日：2018-09-25

Applicant: IDCAPS

Inventor： Pierre BUISSON ,  Carine CHAIGNEAU ,  Jean-Eudes VENDEVILLE

IPC: A61K31/375 ,  B05D1/22 ,  A61K9/50 ,  A23L33/16 ,  A23L33/15 ,  A23L33/115 ,  A23L33/105 ,  A23L29/275 ,  A23L29/262 ,  A23P20/18 ,  A23P10/30 ,  A61K38/44 ,  A23L2/52 ,  A23D9/00

Abstract: Disclosed is a microcapsule including a core having an oxidizable active (OA), the outer part of said core being in a solid form, and a water insoluble coating obtained from an encapsulating agent (EA), with the coating surrounding said core. In particular, the EA can be water soluble or organic solvent soluble, in particular in ethanol. The microcapsule can also include an EA in which the water solubility is pH-dependent. Also, the core does not contain a metal oxide, and the coating does not include a disintegrant, such as sodium starch glycolate. Also disclosed is a process for preparing the microcapsules.