公开(公告)号：US08450524B2

公开(公告)日：2013-05-28

申请号：US13010865

申请日：2011-01-21

申请人： Hui Ting Wang ,  Chia Jung Tsai ,  Chia Hui Shen

发明人： Hui Ting Wang ,  Chia Jung Tsai ,  Chia Hui Shen

IPC分类号： C07C51/56

CPC分类号： C07C51/56 ,  C07C53/12

摘要： The present invention relates to a process for producing carboxylic acid anhydrides by the carbonylation reaction of a carboxylic acid ester, derived from an alcohol and a carboxylic acid, with carbon monoxide containing a small amount of hydrogen in a liquid reaction medium in the presence of a Group VIII B catalyst to produce a carboxylic acid anhydride. The liquid reaction medium comprises the Group VIII B catalyst, an organic halide, the carboxylic acid ester, an alkali metal salt, the carboxylic acid anhydride, the carboxylic acid, N-acetylimidazole as a protecting agent, and ethylidene diacetate (EDA) as an organic promoter. By making use of the protecting agent of N-acetylimidazole, metal ions in the reactor can be prevented from reacting with EDA so as to reduce the formation of hardly-soluble tars during the reaction. Also, the EDA organic promoter is kept at a certain content in the system to promote the overall carbonylation reaction rate.

摘要翻译： 本发明涉及一种通过在醇和羧酸中衍生的羧酸酯与含有少量氢的一氧化碳在液体反应介质中的存在下，通过羰基化反应制备羧酸酐的方法 VIII族B族催化剂生成羧酸酐。 液体反应介质包括VIII族B催化剂，有机卤化物，羧酸酯，碱金属盐，羧酸酐，羧酸，作为保护剂的N-乙酰基咪唑，以及亚乙基二乙酸酯（EDA） 有机促进剂。 通过利用N-乙酰基咪唑的保护剂，可以防止反应器中的金属离子与EDA反应，从而减少反应期间几乎不溶的焦油的形成。 此外，EDA有机促进剂在系统中保持一定含量以促进总的羰基化反应速率。

公开(公告)号：US20120053366A1

公开(公告)日：2012-03-01

申请号：US13010865

申请日：2011-01-21

申请人： Hui Ting Wang ,  Chia Jung Tsai ,  Chia Hui Shen

发明人： Hui Ting Wang ,  Chia Jung Tsai ,  Chia Hui Shen

IPC分类号： C07C51/56

CPC分类号： C07C51/56 ,  C07C53/12

摘要： The present invention relates to a process for producing carboxylic acid anhydrides by the carbonylation reaction of a carboxylic acid ester, derived from an alcohol and a carboxylic acid, with carbon monoxide containing a small amount of hydrogen in a liquid reaction medium in the presence of a Group VIII B catalyst to produce a carboxylic acid anhydride. The liquid reaction medium comprises the Group VIII B catalyst, an organic halide, the carboxylic acid ester, an alkali metal salt, the carboxylic acid anhydride, the carboxylic acid, N-acetylimidazole as a protecting agent, and ethylidene diacetate (EDA) as an organic promoter. By making use of the protecting agent of N-acetylimidazole, metal ions in the reactor can be prevented from reacting with EDA so as to reduce the formation of hardly-soluble tars during the reaction. Also, the EDA organic promoter is kept at a certain content in the system to promote the overall carbonylation reaction rate.

摘要翻译： 本发明涉及一种通过在醇和羧酸中衍生的羧酸酯与含有少量氢的一氧化碳在液体反应介质中的存在下，通过羰基化反应制备羧酸酐的方法 VIII族B族催化剂生成羧酸酐。 液体反应介质包括VIII族B催化剂，有机卤化物，羧酸酯，碱金属盐，羧酸酐，羧酸，作为保护剂的N-乙酰基咪唑，以及亚乙基二乙酸酯（EDA） 有机促进剂。 通过利用N-乙酰基咪唑的保护剂，可以防止反应器中的金属离子与EDA反应，从而减少反应期间几乎不溶的焦油的形成。 此外，EDA有机促进剂在系统中保持一定含量以促进总的羰基化反应速率。