公开(公告)号：US20220031871A1

公开(公告)日：2022-02-03

申请号：US17048072

申请日：2019-04-16

Applicant: Hoffmann-La Roche Inc. ,  Orano Med SAS

Inventor： Julien TORGUE ,  Paul JUREK ,  Federico ROJAS-QUIJANO ,  Garry E. KIEFER ,  Olivier FREYTAG ,  Christian GERDES ,  Christian KLEIN ,  Pablo UMANA ,  Alexander HAAS ,  Sofia FROST ,  Amal SAIDI ,  Tapan NAYAK

IPC: A61K51/04 ,  A61K51/06 ,  A61K51/10 ,  A61P35/00

Abstract: The present application relates to antibodies which bind specifically to chelated radionuclides, including bispecific antibodies, It further relates to the use of such bispecific antibodies in applications such as radioimmunoimaging and radioimmunotherapy. It additionally relates to clearing agents and useful in such methods.