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公开(公告)号：US11673888B2
公开(公告)日：2023-06-13
申请号：US17034240
申请日：2020-09-28
发明人： Jérôme Hert , Daniel Hunziker , Patrizio Mattei , Markus Rudolph , Petra Schmitz , Patrick Di Giorgio
IPC分类号： C07D471/04 , C07D401/14 , A61K9/20 , A61K9/48 , C07D405/14 , C07D495/04 , C07D498/04 , C07D513/04 , C07D519/00
CPC分类号： C07D471/04 , A61K9/2009 , A61K9/2054 , A61K9/2059 , A61K9/2095 , A61K9/485 , A61K9/4858 , A61K9/4866 , C07D401/14 , C07D405/14 , C07D495/04 , C07D498/04 , C07D513/04 , C07D519/00
摘要： The invention provides novel compounds having the general formula (I)
wherein R1, R2, Y, W, A, X, m and n are as defined herein, compositions including the compounds and methods of using the compounds.-
公开(公告)号：US10787459B2
公开(公告)日：2020-09-29
申请号：US16380863
申请日：2019-04-10
发明人： Patrick Di Giorgio , Jerome Hert , Daniel Hunziker , Patrizio Mattei , Markus Rudolph , Petra Schmitz
IPC分类号： A61K31/407 , C07D487/04 , C07D519/00 , A61P27/02
摘要： The invention provides novel compounds having the general formula (I) wherein R1, R2, R9, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
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公开(公告)号：US20180215765A1
公开(公告)日：2018-08-02
申请号：US15933701
申请日：2018-03-23
发明人： Patrick Di Giorgio , Jerome Hert , Daniel Hunziker , Patrizio Mattei , Markus Rudolph , Petra Schmitz , Christoph Ullmer
IPC分类号： C07D487/04 , A61P27/02
CPC分类号： C07D487/04 , A61K31/407 , A61K31/437 , A61K31/5517 , A61P27/02 , C07D471/04
摘要： The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
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公开(公告)号：US20200087307A1
公开(公告)日：2020-03-19
申请号：US16380909
申请日：2019-04-10
发明人： Patrizio Mattei , Jerome Hert , Daniel Hunziker , Markus Rudolph , Petra Schmitz , Patrick Di Giorgio
IPC分类号： C07D487/04 , C07D471/04 , C07D519/00
摘要： The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
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公开(公告)号：US20190300569A1
公开(公告)日：2019-10-03
申请号：US16358371
申请日：2019-03-19
发明人： Konrad Bleicher , Daniella Cheang , Patrick Di Giorgio , Taishan Hu , Patrizio Mattei , Petra Schmitz , Theodor Stoll
IPC分类号： C07K5/09
摘要： The present invention provides compounds of formula (I) wherein X, L1 and R1 to R10 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by Acinetobacter baumannii.
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公开(公告)号：US20180312515A1
公开(公告)日：2018-11-01
申请号：US15933731
申请日：2018-03-23
发明人： Patrizio Mattei , Jerome Hert , Daniel Hunziker , Markus Rudolph , Petra Schmitz , Patrick Di Giorgio
IPC分类号： C07D487/04 , C07D471/04 , C07D519/00
CPC分类号： C07D471/04
摘要： The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
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公开(公告)号：US11819532B2
公开(公告)日：2023-11-21
申请号：US16389292
申请日：2019-04-19
发明人： Konrad Bleicher , Daniella Cheang , Patrick Di Giorgio , Patrizio Mattei , Petra Schmitz , Theodor Stoll
摘要： The present invention provides compounds of formula (I)
wherein X1, X2, R1 to R6 and A are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by bacteria.-
公开(公告)号：US11059794B2
公开(公告)日：2021-07-13
申请号：US16569475
申请日：2019-09-12
发明人： Patrizio Mattei , Jérôme Hert , Daniel Hunziker , Markus Rudolph , Petra Schmitz , Patrick Di Giorgio , Justin Gomme
IPC分类号： C07D257/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/10 , C07D405/12 , C07D405/14 , C07D409/14 , C07D417/14
摘要： The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, X, W, m and n are as defined herein, compositions including the compounds and methods of using the compounds.
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公开(公告)号：US10800786B2
公开(公告)日：2020-10-13
申请号：US16380909
申请日：2019-04-10
发明人： Patrizio Mattei , Jerome Hert , Daniel Hunziker , Markus Rudolph , Petra Schmitz , Patrick Di Giorgio
IPC分类号： C07D487/04 , C07D471/04 , C07D519/00
摘要： The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
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公开(公告)号：US10889588B2
公开(公告)日：2021-01-12
申请号：US16889322
申请日：2020-06-01
发明人： Jerome Hert , Daniel Hunziker , Patrizio Mattei , Markus Rudolph , Petra Schmitz , Christoph Ullmer
IPC分类号： C07D487/04 , A61P27/02 , A61K31/407
摘要： The invention provides novel compounds having the general formula (I) wherein R1, R2, R9, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
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