公开(公告)号：US08389921B2

公开(公告)日：2013-03-05

申请号：US12771778

申请日：2010-04-30

申请人： Hidetoshi Nozaki ,  Fei Wu

发明人： Hidetoshi Nozaki ,  Fei Wu

IPC分类号： H01L27/00 ,  H01J5/16

CPC分类号： H01L27/1464 ,  H01L27/14627 ,  H01L27/14685

摘要： An image sensor in accordance with embodiments disclosed herein includes an array of imaging pixels, an insulator layer, and a plurality of metal reflectors. The array of imaging pixels are disposed within a semiconductor layer, where each imaging pixel in the array of imaging pixels includes a photosensitive element configured to receive light from a backside of the image sensor. The insulator layer is disposed on a frontside of the semiconductor layer and the plurality of metal reflectors are disposed within the insulator layer to reflect the light to a respective photosensitive element. A width of each of the plurality of metal reflectors is equal to a width of a metal reflector at the center of the array multiplied by a scaling factor, where the scaling factor is dependent on a distance of the metal reflector from the center of the array.

摘要翻译： 根据本文公开的实施例的图像传感器包括成像像素阵列，绝缘体层和多个金属反射器。 成像像素阵列设置在半导体层内，其中成像像素阵列中的每个成像像素包括被配置为从图像传感器的背面接收光的感光元件。 绝缘体层设置在半导体层的前侧，并且多个金属反射器设置在绝缘体层内，以将光反射到相应的感光元件。 多个金属反射器中的每一个的宽度等于阵列中心处的金属反射器的宽度乘以比例因子，其中缩放因子取决于金属反射器与阵列的中心的距离 。

公开(公告)号：US08269264B2

公开(公告)日：2012-09-18

申请号：US12615048

申请日：2009-11-09

申请人： Hidetoshi Nozaki ,  Fei Wu

发明人： Hidetoshi Nozaki ,  Fei Wu

IPC分类号： H01L31/062

CPC分类号： H01L27/14605 ,  H01L27/14621 ,  H01L27/14629 ,  H01L27/1464

摘要： An image sensor having an array of pixels disposed in a substrate. Each pixel includes a photosensitive element, a color filter, and waveguide walls. The waveguide walls are disposed in the color filter and surround portions of the color filter to form waveguides through the color filter. The refractive index of the waveguide walls is less than the refractive index of the color filter. The image sensor may be back side illuminated (BSI) or front side illuminated (FSI). In some embodiments, metal walls may be coupled to the waveguide walls.

摘要翻译： 一种具有设置在基板中的像素阵列的图像传感器。 每个像素包括感光元件，滤色器和波导壁。 波导壁设置在滤色器中并且围绕滤色器的部分以形成通过滤色器的波导。 波导壁的折射率小于滤色器的折射率。 图像传感器可以是背面照明（BSI）或前侧照明（FSI）。 在一些实施例中，金属壁可以耦合到波导壁。

公开(公告)号：US20110266421A1

公开(公告)日：2011-11-03

申请号：US12771778

申请日：2010-04-30

申请人： Hidetoshi Nozaki ,  Fei Wu

发明人： Hidetoshi Nozaki ,  Fei Wu

IPC分类号： H01L31/0232 ,  H01L27/146

CPC分类号： H01L27/1464 ,  H01L27/14627 ,  H01L27/14685

摘要： An image sensor in accordance with embodiments disclosed herein includes an array of imaging pixels, an insulator layer, and a plurality of metal reflectors. The array of imaging pixels are disposed within a semiconductor layer, where each imaging pixel in the array of imaging pixels includes a photosensitive element configured to receive light from a backside of the image sensor. The insulator layer is disposed on a frontside of the semiconductor layer and the plurality of metal reflectors are disposed within the insulator layer to reflect the light to a respective photosensitive element. A width of each of the plurality of metal reflectors is equal to a width of a metal reflector at the center of the array multiplied by a scaling factor, where the scaling factor is dependent on a distance of the metal reflector from the center of the array.

摘要翻译： 根据本文公开的实施例的图像传感器包括成像像素阵列，绝缘体层和多个金属反射器。 成像像素阵列设置在半导体层内，其中成像像素阵列中的每个成像像素包括被配置为从图像传感器的背面接收光的感光元件。 绝缘体层设置在半导体层的前侧，并且多个金属反射器设置在绝缘体层内，以将光反射到相应的感光元件。 多个金属反射器中的每一个的宽度等于阵列中心处的金属反射器的宽度乘以比例因子，其中缩放因子取决于金属反射器与阵列的中心的距离 。

公开(公告)号：US20110108938A1

公开(公告)日：2011-05-12

申请号：US12615048

申请日：2009-11-09

申请人： Hidetoshi Nozaki ,  Fei Wu

发明人： Hidetoshi Nozaki ,  Fei Wu

IPC分类号： H01L31/0232 ,  H04N5/335

CPC分类号： H01L27/14605 ,  H01L27/14621 ,  H01L27/14629 ,  H01L27/1464

摘要： An image sensor having an array of pixels disposed in a substrate. Each pixel includes a photosensitive element, a color filter, and waveguide walls. The waveguide walls are disposed in the color filter and surround portions of the color filter to form waveguides through the color filter. The refractive index of the waveguide walls is less than the refractive index of the color filter. The image sensor may be back side illuminated (BSI) or front side illuminated (FSI). In some embodiments, metal walls may be coupled to the waveguide walls.

摘要翻译： 一种具有设置在基板中的像素阵列的图像传感器。 每个像素包括感光元件，滤色器和波导壁。 波导壁设置在滤色器中并且围绕滤色器的部分以形成通过滤色器的波导。 波导壁的折射率小于滤色器的折射率。 图像传感器可以是背面照明（BSI）或前侧照明（FSI）。 在一些实施例中，金属壁可以耦合到波导壁。

公开(公告)号：US08507964B2

公开(公告)日：2013-08-13

申请号：US13591058

申请日：2012-08-21

申请人： Hidetoshi Nozaki ,  Fei Wu

发明人： Hidetoshi Nozaki ,  Fei Wu

IPC分类号： H01L31/062

CPC分类号： H01L27/14605 ,  H01L27/14621 ,  H01L27/14629 ,  H01L27/1464

摘要： An image sensor having an array of pixels disposed in a substrate. The array of pixels includes photosensitive elements, a color filters, and waveguide walls. The waveguide walls are disposed in the color filters and surround portions of the color filters to form waveguides through the color filters. In some embodiments, metal walls may be coupled to the waveguide walls.

摘要翻译： 一种具有设置在基板中的像素阵列的图像传感器。 像素阵列包括光敏元件，滤色器和波导壁。 波导壁设置在滤色器中并且围绕滤色器的周围部分以形成穿过滤色器的波导。 在一些实施例中，金属壁可以耦合到波导壁。

公开(公告)号：US20120313206A1

公开(公告)日：2012-12-13

申请号：US13591058

申请日：2012-08-21

申请人： Hidetoshi Nozaki ,  Fei Wu

发明人： Hidetoshi Nozaki ,  Fei Wu

IPC分类号： H01L27/146

CPC分类号： H01L27/14605 ,  H01L27/14621 ,  H01L27/14629 ,  H01L27/1464

摘要： An image sensor having an array of pixels disposed in a substrate. The array of pixels includes photosensitive elements, a color filters, and waveguide walls. The waveguide walls are disposed in the color filters and surround portions of the color filters to form waveguides through the color filters. In some embodiments, metal walls may be coupled to the waveguide walls.

摘要翻译： 一种具有设置在基板中的像素阵列的图像传感器。 像素阵列包括光敏元件，滤色器和波导壁。 波导壁设置在滤色器中并且围绕滤色器的周围部分以形成穿过滤色器的波导。 在一些实施例中，金属壁可以耦合到波导壁。

公开(公告)号：US09321907B2

公开(公告)日：2016-04-26

申请号：US13990768

申请日：2012-06-04

申请人： Fei Wu ,  Tian Cao ,  Yang Liu ,  Wei Huang ,  Ying Xin Sun

发明人： Fei Wu ,  Tian Cao ,  Yang Liu ,  Wei Huang ,  Ying Xin Sun

IPC分类号： C08K13/00 ,  D21H21/12 ,  B01D19/04 ,  D21H17/00

CPC分类号： C08K13/00 ,  B01D19/0404 ,  D21H17/72 ,  D21H21/12

摘要： Described is a method for preparation of stable fatty alcohol emulsion, wherein, fatty acid esters are introduced into an antifoaming agent emulsion system, and an anionic surfactant is added in the late stage of emulsification process in order to further improve the stability of the emulsion. The anionic surfactant is absorbed to the surface of fatty alcohol particles to make the fatty alcohol emulsion more stable under the action of ionic mutual repulsion. The prepared fatty alcohol emulsion has favorable foam elimination and suppression performance in the paper making procedure, and is stable during storage.

摘要翻译： 描述了稳定的脂肪醇乳液的制备方法，其中将脂肪酸酯引入消泡剂乳液体系中，并且在乳化过程的后期加入阴离子表面活性剂以进一步提高乳液的稳定性。 阴离子表面活性剂被吸收到脂肪醇颗粒的表面，使得脂肪醇乳液在离子相互斥力的作用下更加稳定。 制备的脂肪醇乳液在造纸过程中具有良好的泡沫消除和抑制性能，并且在储存期间是稳定的。

公开(公告)号：US20110213053A1

公开(公告)日：2011-09-01

申请号：US13057267

申请日：2010-09-01

申请人： Fei Wu ,  Zhiping Cao ,  Yingxin Sun ,  Jia Guo ,  Tian Cao ,  Xiang Zhong

发明人： Fei Wu ,  Zhiping Cao ,  Yingxin Sun ,  Jia Guo ,  Tian Cao ,  Xiang Zhong

IPC分类号： C08L63/00

CPC分类号： B01D19/0404 ,  D21H17/53 ,  D21H21/12 ,  D21H23/04

摘要： A new-type papermaking wet-end defoamer and methods of making relating to the field of the chemical preparations for use in papermaking. The defoamer including 5˜99% FAME (fatty acid methyl ester) derivatives having a general structural formula of R1CO(EO)x(PO)yOCH3, molecular weight of 300˜3000 and a turbidity point of 20˜80° C.; which are the products of the addition reaction of FAME as an initiator and EO (ethylene oxide) and/or PO (propylene oxide) under the action of catalyst. The defoamer also including 0.1˜80% polyether having a general structural formula of R2{M(EO)m(PO)nH}a, a molecular weight of 500˜8000 and a turbidity point of 10˜80° C. The defoamer also including a 0.1˜70% modified polyether, with a general structural formula of R2{M(EO)m(PO)nR3}a. The defoamer also including 0.1˜20% natural oil and fat. The new-type papermaking wet-end defoamer is not only applicable to the papermaking wet-end process but also applicable to papermaking wastewater treatment and the elimination of other aqueous foam.

摘要翻译： 一种新型造纸湿式消泡剂，以及与造纸中使用的化学制剂领域相关的制备方法。 消泡剂包括具有通式结构式为R 1 CO（EO）x（PO）y OCH 3，分子量为300〜3000，浊度为20〜80℃的5〜99％FAME（脂肪酸甲酯）衍生物。 它们是在催化剂作用下作为引发剂和EO（环氧乙烷）和/或PO（环氧丙烷）的加成反应的产物。 消泡剂还包括具有通式结构式为R 2（M（EO）m（PO）n H} a的0.1〜80％的聚醚，分子量为500〜8000，浊点为10〜80℃。消泡剂也 包括具有通式结构式为R 2 {M（EO）m（PO）n R 3} a的0.1〜70％的改性聚醚。 消泡剂中还含有0.1〜20％天然油脂。 新型造纸湿式消泡剂不仅适用于造纸湿端工艺，而且适用于造纸废水处理和其他水性泡沫的消除。

公开(公告)号：US09689041B2

公开(公告)日：2017-06-27

申请号：US14007439

申请日：2012-03-23

申请人： Xun Ye ,  Fei Wu ,  Qinghua Xu ,  Fang Liu ,  Xia Meng ,  Bruno Mougin

发明人： Xun Ye ,  Fei Wu ,  Qinghua Xu ,  Fang Liu ,  Xia Meng ,  Bruno Mougin

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/158

摘要： The present invention provides a method for determining in vitro, in a peripheral blood sample, the probability for an individual to suffer from a colorectal cancer, using the comparison of the amount of expression products of nucleic acids of genes of the individual to be tested with the amount of expression products of nucleic acids of the same genes obtained from a CRC group of patients constituting the positive control and with the amount of expression products of nucleic acids of the same genes obtained from a CNC group of individuals constituting the negative control; and a kit comprising specific binding partners for said expression products.

公开(公告)号：US09410188B2

公开(公告)日：2016-08-09

申请号：US13696937

申请日：2010-05-28

申请人： Xun Ye ,  Fei Wu ,  Qinghua Xu ,  Xia Meng ,  Bruno Mougin

发明人： Xun Ye ,  Fei Wu ,  Qinghua Xu ,  Xia Meng ,  Bruno Mougin

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6837 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158

摘要： A method and kit are related to discriminating between breast cancer and benign breast disease by the determination of the expression level of at least one target gene including a nucleic acid sequence selected from the nucleic acid sequences set forth in SEQ ID NOs: 1, 2 or 3, 4 and 5 or 6 to obtain an expression profile for the patient, and the comparison of the expression profile of the patient with expression profiles of target genes from patients previously clinically classified as breast cancer and expression profiles of target genes from patients previously clinically classified as benign breast disease.

摘要翻译： 一种方法和试剂盒涉及通过测定至少一种靶基因的表达水平来区分乳腺癌和良性乳腺疾病，所述至少一种靶基因包括选自SEQ ID NO：1,2所示的核酸序列的核酸序列，或 3,4和5或6以获得患者的表达谱，并且将患者的表达谱与先前临床分类为乳腺癌的患者的靶基因的表达谱和先前临床患者的靶基因的表达谱进行比较 归为良性乳腺疾病。