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公开(公告)号：US4771069A
公开(公告)日：1988-09-13
申请号：US13519
申请日：1987-02-11
IPC分类号： C07D337/14 , A61K31/38 , C07D409/12
CPC分类号： C07D337/14
摘要： Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.
摘要翻译： 公开了新型氨基烷基硫代二苯并硫蛋白及其相关化合物，其生理上可耐受的酸加成盐，其制备方法，包括其的药物和兽用制剂以及通过施用方法进行治疗。 这些化合物可用作抗抑郁药，止痛剂和抗惊厥剂。
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公开(公告)号：US5140027A
公开(公告)日：1992-08-18
申请号：US522932
申请日：1990-05-14
IPC分类号： C07D313/14
CPC分类号： C07D313/14
摘要： Novel aminoalkylthiodibenzoxepins, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as analgesic, antidepressant and anticonvulsant agents. A process for selectively reducing olefins by alkaline earth metals in loweralkanols is also disclosed.
摘要翻译： 公开了新的氨基烷基硫代二氧化硫蛋白，其生理上可耐受的酸加成盐，其制备方法，包括其的药物和兽医制剂以及通过施用方法进行治疗。 这些化合物可用作镇痛药，抗抑郁药和抗惊厥药。 还公开了一种通过碱金属在低级烷醇中选择性还原烯烃的方法。
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公开(公告)号：US4943571A
公开(公告)日：1990-07-24
申请号：US335354
申请日：1989-04-10
IPC分类号： C07D313/14
CPC分类号： C07D313/14
摘要： Novel aminoalkylthiodibenzoxepins, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as analgesic, antidepressant and anticonvulsant agents. A process for selectively reducing olefins by alkaline earth metals in loweralkanols is also disclosed.
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公开(公告)号：US4775683A
公开(公告)日：1988-10-04
申请号：US14748
申请日：1987-02-13
IPC分类号： C07D337/14 , A61K31/38
CPC分类号： C07D337/14
摘要： Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.
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5.发明授权
公开(公告)号：US4524207A
公开(公告)日：1985-06-18
申请号：US515969
申请日：1983-07-21
IPC分类号： C07D211/52 , C07D211/54 , C07D495/10 , C07D513/10
CPC分类号： C07D495/10 , C07D211/52 , C07D211/54
摘要： Novel substituted 1,3-dihydrospiro[benzo(c)thiophene]s and methods of preparing the same are described. These compounds are useful as antidepressants and tranquilizers and intermediates therefor.
摘要翻译： 描述了新型取代的1,3-二氢螺[苯并（c）噻吩]及其制备方法。 这些化合物可用作抗抑郁药和镇定剂及其中间体。
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公开(公告)号：US5216178A
公开(公告)日：1993-06-01
申请号：US745623
申请日：1991-08-15
IPC分类号： C07D313/14
CPC分类号： C07D313/14
摘要： Novel aminoalkylthiodibenzoxepins, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as analgesic, antidepressant and anticonvulsant agents. A process for selectively reducing olefins by alkaline earth metals in loweralkanols is also disclosed.
摘要翻译： 公开了新的氨基烷基硫代二氧化硫蛋白，其生理上可耐受的酸加成盐，其制备方法，包括其的药物和兽医制剂以及通过施用方法进行治疗。 这些化合物可用作镇痛药，抗抑郁药和抗惊厥药。 还公开了一种通过碱金属在低级烷醇中选择性还原烯烃的方法。
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公开(公告)号：US5006664A
公开(公告)日：1991-04-09
申请号：US453872
申请日：1989-12-20
IPC分类号： C07D337/14
CPC分类号： C07D337/14
摘要： Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.
摘要翻译： 公开了新型氨基烷基硫代二苯并硫蛋白及其相关化合物，其生理上可耐受的酸加成盐，其制备方法，包括其的药物和兽用制剂以及通过施用方法进行治疗。 这些化合物可用作抗抑郁药，止痛剂和抗惊厥剂。
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公开(公告)号：US4775682A
公开(公告)日：1988-10-04
申请号：US14740
申请日：1987-02-13
IPC分类号： C07D337/14 , A61K31/38
CPC分类号： C07D337/14
摘要： Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.
摘要翻译： 公开了新型氨基烷基硫代二苯并硫蛋白及其相关化合物，其生理上可耐受的酸加成盐，其制备方法，包括其的药物和兽用制剂以及通过施用方法进行治疗。 这些化合物可用作抗抑郁药，止痛剂和抗惊厥剂。
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9.发明授权Antidepressive and tranquilizing substituted 1,3-dihydrospiro[benzo(c)thiophene]s 失效抗抑郁和镇定取代的1,3-二氢螺[苯并（c）噻吩]
公开(公告)号：US4409229A
公开(公告)日：1983-10-11
申请号：US313169
申请日：1981-10-20
IPC分类号： C07D211/52 , C07D211/54 , C07D495/10 , A61K31/445 , A61K31/40
CPC分类号： C07D495/10 , C07D211/52 , C07D211/54
摘要： Novel substituted 1,3-dihydrospiro[benzo(c)thiophene]s and methods of preparing the same are described. These compounds are useful as antidepressants and tranquilizers and intermediates therefor.
摘要翻译： 描述了新型取代的1,3-二氢螺[苯并（c）噻吩]及其制备方法。 这些化合物可用作抗抑郁药和镇定剂及其中间体。
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公开(公告)号：US4837227A
公开(公告)日：1989-06-06
申请号：US738507
申请日：1985-05-28
IPC分类号： C07D313/14
CPC分类号： C07D313/14
摘要： Novel aminoalkylthiodibenzoxepins, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as analgesic, antidepressant and anticonvulsant agents. A process for selectively reducing olefins by alkaline earth metals in loweralkanols is also disclosed.
摘要翻译： 公开了新的氨基烷基硫代二氧化硫蛋白，其生理上可耐受的酸加成盐，其制备方法，包括其的药物和兽医制剂以及通过施用方法进行治疗。 这些化合物可用作镇痛药，抗抑郁药和抗惊厥药。 还公开了一种通过碱金属在低级烷醇中选择性还原烯烃的方法。
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