公开(公告)号：US20220335859A1

公开(公告)日：2022-10-20

申请号：US17810735

申请日：2022-07-05

申请人： HeartFlow, Inc.

发明人： Sethuraman SANKARAN ,  Christopher ZARINS ,  Charles A. TAYLOR ,  Leo GRADY

IPC分类号： G09B23/30 ,  G16H50/50 ,  G16H50/20 ,  G09B9/00

摘要： Systems and methods are disclosed for identifying and modeling unresolved vessels, and the effects thereof, in image-based patient-specific hemodynamic models. One method includes: receiving a patient-specific anatomical model of at least a portion of a visceral vascular system of the patient; receiving patient-specific information related to the patient's food intake; generating a patient-specific model of blood flow in the patient-specific anatomical model of the portion of the visceral vascular system of the patient; generating a patient-specific model of nutrient transport from at least a part of a gastrointestinal system of the patient to the portion of the visceral vascular system of the patient based on the patient-specific information related to the patient's food intake; and determining an indicia of energy available in the patient based on the patient-specific model of nutrient transport.

公开(公告)号：US20230210602A1

公开(公告)日：2023-07-06

申请号：US18185445

申请日：2023-03-17

申请人： HeartFlow, Inc.

发明人： Sethuraman SANKARAN ,  Christopher ZARINS ,  Leo GRADY

IPC分类号： G16H50/50 ,  A61B5/02 ,  G16H50/30

CPC分类号： G16H50/50 ,  A61B5/02007 ,  G16H50/30 ,  G06T2207/30104

摘要： A computer implemented method for assessing an arterio-venous malformation (AVM) may include, for example, receiving a patient-specific model of a portion of an anatomy of a patient; using a computer processor to analyze the patient-specific model for identifying one or more blood vessels associated with the AVM, in the patient-specific model; and estimating a risk of an undesirable outcome caused by the AVM, by performing computer simulations of blood flow through the one or more blood vessels associated with the AVM in the patient-specific model.

公开(公告)号：US20210093384A1

公开(公告)日：2021-04-01

申请号：US17106987

申请日：2020-11-30

申请人： HeartFlow, Inc.

发明人： Leo GRADY ,  Charles A. TAYLOR ,  Christopher ZARINS

IPC分类号： A61B34/10 ,  G16H50/50 ,  G06T7/11 ,  A61B5/026 ,  A61B6/03 ,  A61B6/00 ,  A61B8/06 ,  G06T7/00 ,  G09B9/00 ,  G09B23/30

摘要： Systems and methods are disclosed for assessing organ and/or tissue transplantation by estimating blood flow through a virtual transplant model by receiving a patient-specific anatomical model of the intended transplant recipient; receiving a patient-specific anatomical model of the intended transplant donor, the model including the vasculature of the organ or tissue that is intended to be transplanted to the recipient; constructing a unified model of the connected system post transplantation, the connected system including the transplanted organ or tissue from the intended transplant donor and the vascular system of the intended transplant recipient; receiving one or more blood flow characteristics of the connected system; assessing the suitability for an actual organ or tissue transplantation using the received blood flow characteristics; and outputting the assessment into an electronic storage medium or display.

公开(公告)号：US20160314601A1

公开(公告)日：2016-10-27

申请号：US14842960

申请日：2015-09-02

申请人： HeartFlow, Inc.

发明人： Sethuraman SANKARAN ,  Christopher ZARINS ,  Leo J. GRADY

IPC分类号： G06T11/00 ,  G06T7/00 ,  G06T7/20 ,  A61B19/00

CPC分类号： A61B34/10 ,  A61B5/0035 ,  A61B5/0073 ,  A61B5/02007 ,  A61B5/055 ,  A61B5/4848 ,  A61B5/7275 ,  A61B2034/105 ,  A61B2505/05 ,  G06F19/00 ,  G06T7/0012 ,  G06T7/20 ,  G06T11/003 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/30104 ,  G16H50/30 ,  G16H50/50

摘要： A computer implemented method for assessing an arterio-venous malformation (AVM) may include, for example, receiving a patient-specific model of a portion of an anatomy of a patient; using a computer processor to analyze the patient-specific model for identifying one or more blood vessels associated with the AVM, in the patient-specific model; and estimating a risk of an undesirable outcome caused by the AVM, by performing computer simulations of blood flow through the one or more blood vessels associated with the AVM in the patient-specific model.

摘要翻译： 用于评估动静脉畸形（AVM）的计算机实现的方法可以包括例如接收患者的解剖结构的一部分的患者特定模型; 使用计算机处理器在患者特异性模型中分析用于识别与AVM相关联的一个或多个血管的患者特异性模型; 以及通过对患者特定模型中与AVM相关联的一个或多个血管进行血流的计算机模拟来估计由AVM引起的不期望的结果的风险。

公开(公告)号：US20220110690A1

公开(公告)日：2022-04-14

申请号：US17644762

申请日：2021-12-16

申请人： HeartFlow, Inc.

发明人： Sethuraman SANKARAN ,  Christopher ZARINS ,  Leo GRADY

IPC分类号： A61B34/10 ,  A61B5/02 ,  A61B5/00 ,  G16H50/30 ,  G16H50/50 ,  G06T7/00 ,  G06T7/20 ,  G06T11/00 ,  G16H30/40

摘要： A computer implemented method for assessing an arterio-venous malformation (AVM) may include, for example, receiving a patient-specific model of a portion of an anatomy of a patient; using a computer processor to analyze the patient-specific model for identifying one or more blood vessels associated with the AVM, in the patient-specific model; and estimating a risk of an undesirable outcome caused by the AVM, by performing computer simulations of blood flow through the one or more blood vessels associated with the AVM in the patient-specific model.

公开(公告)号：US20180047304A1

公开(公告)日：2018-02-15

申请号：US15673637

申请日：2017-08-10

申请人： HeartFlow, Inc.

发明人： Sethuraman SANKARAN ,  Christopher ZARINS ,  Charles A. TAYLOR ,  Leo GRADY

IPC分类号： G09B23/30 ,  G06F19/00 ,  G09B9/00

CPC分类号： G09B23/303 ,  G06F19/3475 ,  G06N5/048 ,  G06N20/00 ,  G09B9/00 ,  G16H50/20 ,  G16H50/50

摘要： Systems and methods are disclosed for identifying and modeling unresolved vessels, and the effects thereof, in image-based patient-specific hemodynamic models. One method includes: receiving a patient-specific anatomical model of at least a portion of a visceral vascular system of the patient; receiving patient-specific information related to the patient's food intake; generating a patient-specific model of blood flow in the patient-specific anatomical model of the portion of the visceral vascular system of the patient; generating a patient-specific model of nutrient transport from at least a part of a gastrointestinal system of the patient to the portion of the visceral vascular system of the patient based on the patient-specific information related to the patient's food intake; and determining an indicia of energy available in the patient based on the patient-specific model of nutrient transport.

公开(公告)号：US20170161455A1

公开(公告)日：2017-06-08

申请号：US15367885

申请日：2016-12-02

申请人： HeartFlow, Inc.

发明人： Leo GRADY ,  Christopher ZARINS ,  Edward Karl HAHN, III ,  Ying BAI ,  Sethuraman SANKARAN ,  Peter Kersten PETERSEN ,  Michiel SCHAAP

IPC分类号： G06F19/00 ,  A61B5/00

CPC分类号： G16H50/50 ,  A61B5/4842 ,  A61B5/4848 ,  A61B5/7271 ,  A61B5/742 ,  A61B2576/00 ,  G06F19/00 ,  G06F19/321 ,  G06T7/0016 ,  G16H10/60

摘要： Systems and methods are disclosed for associating medical images with a patient. One method includes: receiving two or more medical images of patient anatomy in an electronic storage medium; generating an anatomical model for each of the received medical images; comparing the generated anatomical models; determining a score assessing the likelihood that the two or more medical images belong to the same patient, using the comparison of the generated anatomical models; and outputting the score to an electronic storage medium or display.