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公开(公告)号：US20230405093A1
公开(公告)日：2023-12-21
申请号：US18036580
申请日：2021-11-15
发明人： Jae Hyuk CHOI , Jin Young KIM , Cho Rong PARK , Sang Yun KIM , Jeong A KIM , Doo Seo JANG
CPC分类号： A61K38/47 , A61P13/12 , C12Y302/01022
摘要： The present invention relates to use of a fusion protein of a therapeutic enzyme and an immunoglobulin Fc region in the prevention or improvement of renal diseases caused by or accompanied by Fabry disease.
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公开(公告)号：US20230124171A1
公开(公告)日：2023-04-20
申请号：US17915808
申请日：2021-03-31
发明人： Euh Lim OH , Sang Yun KIM , Yong Ho HEO , Jin Young KIM , Cho Rong PARK , Jun Sub PARK , Hyun Soo RYU
摘要： The present invention relates to changes in interleukin-2 alpha receptors and interleukin-2 analogs with increased binding affinity for interleukin-2 beta receptors.
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公开(公告)号：US20230348550A1
公开(公告)日：2023-11-02
申请号：US18349656
申请日：2023-07-10
发明人： Euh Lim OH , Sang Yun KIM , Yong Ho HEO , Jin Young KIM , Cho Rong PARK , Jun Sub PARK , Hyun Soo RYU
CPC分类号： C07K14/55 , G01N33/6869
摘要： Modifications to interleukin-2 alpha receptors are disclosed. Interleukin-2 analogs with increased binding affinity for interleukin-2 beta receptors are disclosed.
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4.发明公开公开(公告)号：US20230416714A1
公开(公告)日：2023-12-28
申请号：US18036538
申请日：2021-11-15
发明人： Jin Young KIM , Cho Rong PARK , Sang Yun KIM , Won Ki KIM , Su Yeon PARK
CPC分类号： C12N9/2465 , A61P25/02 , C07K2319/30
摘要： A use of a fusion protein of a therapeutic enzyme and an immunoglobulin Fe region is disclosed. The fusion protein is represented by the following chemical formula 1. The fusion protein shows protective effects on peripheral sensory nerves and exhibits an extended duration in the body. Thus, the fusion protein or a composition containing the fusion protein can be used in the prevention or improvement of neuropathy.
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