公开(公告)号：US20240425521A1

公开(公告)日：2024-12-26

申请号：US18679695

申请日：2024-05-31

Applicant: H. Lundbeck A/S

Inventor： Karsten Juhl ,  Wanwan Yu ,  Thomas Leegaard Andersen ,  Erhad Ascic ,  Michael Baek ,  Gitte Kobberøe Mikkelsen ,  Andreas Michael Arnold ,  Anders Højgaard Hansen ,  Petra Lindovská ,  Henrik Juhani Keränen ,  Ferran Planas Padrós

IPC: C07D498/14 ,  A61K31/424 ,  A61K31/4245 ,  A61K31/429 ,  A61K31/437 ,  A61K31/519 ,  C07D498/04 ,  C07D513/04

Abstract: The present invention relates to novel spiro-macrocyclic compounds of general formula (I) which are Orexin 2 receptor agonists.