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公开(公告)号：US07910137B2
公开(公告)日：2011-03-22
申请号：US11483410
申请日：2006-07-07
IPC分类号： A61K33/24 , A61K33/34 , A61K33/32 , A61K33/26 , A61K9/48 , A61K9/20 , A61K31/28 , A61K31/30 , A61K31/295 , A61K31/315 , A01N59/16
CPC分类号： C07F9/005 , A23L33/165 , A23L33/175 , A61K31/28 , A61K31/30 , A61K31/315 , A61K31/51 , A61K31/555 , C07C229/76 , C07F1/005 , C07F3/003 , C07F11/005 , C07F15/025
摘要： Metal carnitine chelates comprising carnitine chelated to a nutritionally relevant metal can be used for general nutrition as well as well as to treat a variety of health related problems and symptoms. For example, metal carnitine chelates can be used to maintain good cardiovascular health, increase male fertility, enhance weight loss, provide mineral and/or carnitine supplements for mineral- and/or carnitine-deficient subjects, and reduce alcohol dependency and associated symptoms. Nutritionally relevant metals that can be used include copper, zinc, magnesium, calcium, iron, chromium, and manganese, to name a few.
摘要翻译： 包含与营养相关金属螯合的肉碱的金属肉碱螯合物可用于一般营养以及治疗各种与健康有关的问题和症状。 例如，金属肉碱螯合物可用于维持良好的心血管健康状况，增加男性生殖力，增强体重减轻，为矿物和/或肉碱缺乏的受试者提供矿物质和/或肉碱补充剂，并减少酒精依赖性和相关症状。 可以使用的营养相关金属包括铜，锌，镁，钙，铁，铬和锰，仅举几例。
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公开(公告)号：US20120022162A1
公开(公告)日：2012-01-26
申请号：US13189893
申请日：2011-07-25
IPC分类号： A61K31/198 , A23L1/304 , A23L2/52 , A23L1/05 , C07F15/00 , C07F9/00 , C07F13/00 , C07F11/00 , C07F1/00 , C07F3/00 , A23L1/305 , C07C229/24
CPC分类号： A23L33/175 , A23L33/16 , A23L33/165 , A23V2002/00 , A23V2250/1592 , A23V2250/1628 , A23V2250/044 , A23V2250/061 , A23V2250/0622
摘要： Mixed amino acid/mineral compounds can include at least two amino acids bound to a central mineral atom. The combination of amino acids can be tailored to provide improved solubility, absorption, and/or bioavailability of the mineral. Optionally, organic acids can be bound to the mineral or combined with the chelate in order to further improve solubility, absorption, and/or bioavailability. Compositions including one or more mixed amino acid/mineral compounds can be included in therapeutic regimens for indications in which the mineral may treat and/or prevent a condition or symptom.
摘要翻译： 混合的氨基酸/矿物化合物可包括与中心矿物原子结合的至少两个氨基酸。 可以调整氨基酸的组合以提供矿物质的改善的溶解度，吸收和/或生物利用度。 任选地，有机酸可以与矿物结合或与螯合物结合，以进一步改善溶解度，吸收和/或生物利用度。 包括一种或多种混合氨基酸/矿物化合物的组合物可以包括在用于矿物可以治疗和/或预防病症或症状的适应症的治疗方案中。
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公开(公告)号：US20150030698A1
公开(公告)日：2015-01-29
申请号：US14444780
申请日：2014-07-28
申请人： R. Charles Thompson
发明人： R. Charles Thompson
IPC分类号： A61K31/198 , A23L1/304 , A23L2/52 , A23L1/305 , A61K33/30 , A61K31/197
CPC分类号： A61K31/198 , A23L2/39 , A23L2/52 , A23L33/16 , A23L33/175 , A61K31/197
摘要： An oral product that includes an amino acid nitric oxide precursor and a compound capable of providing zinc ions. The product can be formulated as a powder and mixed with a liquid in preparation for consumption by a person. The powdered formulation may be mixed with water followed by a brief but necessary allotment of time for the powdered formulation to completely react in the water. The resulting beverage may then be consumed by a person or user to facilitate production of nitric oxide and creatine-phosphate that is usable by the person, especially to help recover and rejuvenate the person after physical exertion and reduce or relieve muscle soreness.
摘要翻译： 一种包含氨基酸一氧化氮前体和能够提供锌离子的化合物的口服产品。 该产品可以配制成粉末并与液体混合，以备人们消费。 粉末制剂可以与水混合，然后短时间但必要的时间分配粉末制剂在水中完全反应。 所得到的饮料然后可以被人或用户消耗以促进人可使用的一氧化氮和肌酸磷酸盐的产生，特别是有助于在体力消耗后恢复和恢复人体，并减轻或缓解肌肉酸痛。
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公开(公告)号：US09433597B2
公开(公告)日：2016-09-06
申请号：US14444780
申请日：2014-07-28
申请人： R. Charles Thompson
发明人： R. Charles Thompson
IPC分类号： A61K31/198 , A61K31/197 , A23L2/52 , A23L1/305 , A23L1/304 , A23L2/39
CPC分类号： A61K31/198 , A23L2/39 , A23L2/52 , A23L33/16 , A23L33/175 , A61K31/197
摘要： An oral product that includes an amino acid nitric oxide precursor and a compound capable of providing zinc ions. The product can be formulated as a powder and mixed with a liquid in preparation for consumption by a person. The powdered formulation may be mixed with water followed by a brief but necessary allotment of time for the powdered formulation to completely react in the water. The resulting beverage may then be consumed by a person or user to facilitate production of nitric oxide and creatine-phosphate that is usable by the person, especially to help recover and rejuvenate the person after physical exertion and reduce or relieve muscle soreness.
摘要翻译： 一种包含氨基酸一氧化氮前体和能够提供锌离子的化合物的口服产品。 该产品可以配制成粉末并与液体混合，以备人们消费。 粉末制剂可以与水混合，然后短时间但必要的时间分配粉末制剂在水中完全反应。 所得到的饮料然后可以被人或用户消耗以促进人可使用的一氧化氮和肌酸磷酸盐的产生，特别是有助于在体力消耗后恢复和恢复人体，并减轻或缓解肌肉酸痛。
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5.发明授权Method for quantitatively determining unbound metal in formulations containing chelates 有权用于定量测定含螯合物的制剂中未结合金属的方法公开(公告)号：US07946155B2
公开(公告)日：2011-05-24
申请号：US12181874
申请日：2008-07-29
IPC分类号： G01N33/20
CPC分类号： G01N30/96 , G01N30/88 , G01N2030/8809
摘要： Methods are provided for quantitatively determining the amount of unbound metal present in a sample suspected of containing a metal-ligand chelate.
摘要翻译： 提供了用于定量测定怀疑含有金属 - 配体螯合物的样品中存在的未结合金属的量的方法。
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公开(公告)号：US08425956B2
公开(公告)日：2013-04-23
申请号：US13189893
申请日：2011-07-25
IPC分类号： A23L1/305
CPC分类号： A23L33/175 , A23L33/16 , A23L33/165 , A23V2002/00 , A23V2250/1592 , A23V2250/1628 , A23V2250/044 , A23V2250/061 , A23V2250/0622
摘要： Mixed amino acid/mineral compounds can include at least two amino acids bound to a central mineral atom. The combination of amino acids can be tailored to provide improved solubility, absorption, and/or bioavailability of the mineral. Optionally, organic acids can be bound to the mineral or combined with the chelate in order to further improve solubility, absorption, and/or bioavailability. Compositions including one or more mixed amino acid/mineral compounds can be included in therapeutic regimens for indications in which the mineral may treat and/or prevent a condition or symptom.
摘要翻译： 混合的氨基酸/矿物化合物可包括与中心矿物原子结合的至少两个氨基酸。 可以调整氨基酸的组合以提供矿物质的改善的溶解度，吸收和/或生物利用度。 任选地，有机酸可以与矿物结合或与螯合物结合，以进一步改善溶解度，吸收和/或生物利用度。 包括一种或多种混合氨基酸/矿物化合物的组合物可以包括在用于矿物可以治疗和/或预防病症或症状的适应症的治疗方案中。
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公开(公告)号：US08007846B2
公开(公告)日：2011-08-30
申请号：US11623476
申请日：2007-01-16
IPC分类号： A23L1/304
CPC分类号： A23L33/175 , A23L33/16 , A23L33/165 , A23V2002/00 , A23V2250/1592 , A23V2250/1628 , A23V2250/044 , A23V2250/061 , A23V2250/0622
摘要： Mixed amino acid/mineral compounds can include at least two amino acids bound to a central mineral atom. The combination of amino acids can be tailored to provide improved solubility, absorption, and/or bioavailability of the mineral. Optionally, organic acids can be bound to the mineral or combined with the chelate in order to further improve solubility, absorption, and/or bioavailability. Compositions including one or more mixed amino acid/mineral compounds can be included in therapeutic regimens for indications in which the mineral may treat and/or prevent a condition or symptom.
摘要翻译： 混合的氨基酸/矿物化合物可包括与中心矿物原子结合的至少两个氨基酸。 可以调整氨基酸的组合以提供矿物质的改善的溶解度，吸收和/或生物利用度。 任选地，有机酸可以与矿物结合或与螯合物结合，以进一步改善溶解度，吸收和/或生物利用度。 包括一种或多种混合氨基酸/矿物化合物的组合物可以包括在用于矿物可以治疗和/或预防病症或症状的适应症的治疗方案中。
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8.发明申请公开(公告)号：US20090071232A1
公开(公告)日：2009-03-19
申请号：US12181874
申请日：2008-07-29
IPC分类号： G01N33/20
CPC分类号： G01N30/96 , G01N30/88 , G01N2030/8809
摘要： Methods are provided for quantitatively determining the amount of unbound metal present in a sample suspected of containing a metal-ligand chelate.
摘要翻译： 提供了用于定量测定怀疑含有金属 - 配体螯合物的样品中存在的未结合金属的量的方法。
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