公开(公告)号：US20230065984A1

公开(公告)日：2023-03-02

申请号：US17464589

申请日：2021-09-01

Applicant: Global Life Sciences Solutions USA LLC

Inventor： Douglas Albagli ,  William A. Hennessy ,  Ralph Stankowski

IPC: C12M1/00 ,  B01D69/10 ,  B01D71/64 ,  B01D69/02

Abstract: Filter holders and membranes are provided that can be included within a bioreactor bag system. The filter holders and membranes include features that allow incorporation of advanced membrane materials having differing material characteristics than traditional membranes that more closely matched the characteristics of the filter holder.

公开(公告)号：US11439959B2

公开(公告)日：2022-09-13

申请号：US16842402

申请日：2020-04-07

Applicant: GLOBAL LIFE SCIENCES SOLUTIONS USA LLC

Inventor： William A Hennessy ,  Douglas Albagli

IPC: B01D71/64 ,  B01D67/00 ,  G03F7/00 ,  B01D69/06 ,  B01D69/10

Abstract: Porous membranes are provided according to the invention having desirable coefficient of thermal expansion and large surface area, for example at least about 4,000 mm2. These porous membranes may be made according to an exemplary process employing lithographic patterning of a photoresist followed by development of the photoresist and etching. In one aspect, the etch barrier layer is chosen from a material that does not react with or incorporate metal or other contaminants into the membrane layer.

公开(公告)号：US12036514B2

公开(公告)日：2024-07-16

申请号：US17219713

申请日：2021-03-31

Applicant: Global Life Sciences Solutions USA LLC

Inventor： Douglas Albagli ,  William A Hennessy ,  Samrat Chawda ,  Robert Gallup

IPC: B01D67/00 ,  B01D61/14 ,  G03F7/00 ,  G03F7/11

CPC classification number: B01D67/0034 ,  B01D61/147 ,  G03F7/0015 ,  G03F7/11 ,  B01D2323/24 ,  B01D2323/42

Abstract: Porous liquid-filtering membranes having a repeatable distribution of pores of a small dimension are provided, as well as pillar templates that are used to produce such liquid filtering membranes. Also disclosed are methods of making and using the pillar templates to make porous liquid filtering membranes.

公开(公告)号：US20240050905A1

公开(公告)日：2024-02-15

申请号：US18494333

申请日：2023-10-25

Applicant: Global Life Sciences Solutions USA LLC

Inventor： Ralph Stankowski ,  Douglas Albagli ,  William A. Hennessy

IPC: B01D71/06 ,  B01D67/00 ,  B01D69/02

CPC classification number: B01D71/06 ,  B01D67/0037 ,  B01D69/02 ,  B01D2325/04

Abstract: A biocompatible polymeric membrane includes pores defined between two material layers, where the first membrane material layer includes strips, and the second membrane material binds to each of the plurality of first membrane material layer strips includes a plurality of windows exposing each of the first membrane material strips. The biocompatible polymeric filtration membrane comprises pores defined by uniform passages defined by the first membrane material layer strips and the second membrane material layer within each window.

公开(公告)号：US20230364564A1

公开(公告)日：2023-11-16

申请号：US18246153

申请日：2021-10-05

Applicant: Global Life Sciences Solutions USA LLC

Inventor： William A. Hennessy ,  Douglas Albagli ,  Ralph Stankowski

IPC: B01D71/64 ,  B01D67/00 ,  B01D69/02

CPC classification number: B01D71/64 ,  B01D67/0037 ,  B01D67/0093 ,  B01D69/02 ,  B01D2325/04

Abstract: A biocompatible polymeric membrane includes pores (106) defined between two material layers, where the first membrane material layer (101) includes strips, and the second membrane material (104) binds to each of the plurality of first membrane material layer strips (101) includes a plurality of windows (105) exposing each of the first membrane material strips (101). The biocompatible polymeric filtration membrane comprises pores (106) defined by uniform passages defined by the first membrane material layer strips (101) and the second membrane material layer (104) within each window (105).

公开(公告)号：US12172138B2

公开(公告)日：2024-12-24

申请号：US17883692

申请日：2022-08-09

Applicant: GLOBAL LIFE SCIENCES SOLUTIONS USA, LLC

Inventor： William A Hennessy ,  Douglas Albagli

IPC: B01D71/64 ,  B01D67/00 ,  B01D69/06 ,  B01D69/10 ,  G03F7/00

Abstract: Porous membranes are provided according to the invention having desirable coefficient of thermal expansion and large surface area, for example at least about 4,000 mm2. These porous membranes may be made according to an exemplary process employing lithographic patterning of a photoresist followed by development of the photoresist and etching. In one aspect, the etch barrier layer is chosen from a material that does not react with or incorporate metal or other contaminants into the membrane layer.

公开(公告)号：US11786869B2

公开(公告)日：2023-10-17

申请号：US16842448

申请日：2020-04-07

Applicant: GLOBAL LIFE SCIENCES SOLUTIONS USA LLC

Inventor： William A Hennessy ,  Douglas Albagli

IPC: B01D67/00 ,  B01D69/02 ,  B01D71/64

CPC classification number: B01D67/0034 ,  B01D69/02 ,  B01D71/64 ,  B01D2325/04 ,  B01D2325/08

Abstract: Porous membranes are provided according to the invention having desirable coefficient of thermal expansion and large surface area, for example at least about 4,000 mm2. These porous membranes may be made according to an exemplary process employing lithographic patterning of a photoresist followed by development of the photoresist and etching. In one aspect, the etch barrier layer is chosen from a material that does not react with or incorporate metal or other contaminants into the membrane layer.

公开(公告)号：US20230066039A1

公开(公告)日：2023-03-02

申请号：US17464549

申请日：2021-09-01

Applicant: Global Life Sciences Solutions USA LLC

Inventor： Douglas Albagli ,  William A. Hennessy ,  Ralph Stankowski

IPC: C12M1/00 ,  B01D71/64 ,  B01D69/02

Abstract: Filter holders and membranes are provided that can be included within a bioreactor bag system. The filter holders and membranes include features that allow incorporation of advanced membrane materials having differing material characteristics than traditional membranes that more closely matched the characteristics of the filter holder.

公开(公告)号：US20220111338A1

公开(公告)日：2022-04-14

申请号：US17067528

申请日：2020-10-09

Applicant: Global Life Sciences Solutions USA LLC

Inventor： Ralph Stankowski ,  Douglas Albagli ,  William A. Hennessy

IPC: B01D71/64 ,  B01D67/00 ,  B01D69/02

Abstract: A biocompatible polymeric membrane includes pores defined between two material layers, where the first membrane material layer includes strips, and the second membrane material binds to each of the plurality of first membrane material layer strips includes a plurality of windows exposing each of the first membrane material strips. The biocompatible polymeric filtration membrane comprises pores defined by uniform passages defined by the first membrane material layer strips and the second membrane material layer within each window.

公开(公告)号：US12172134B2

公开(公告)日：2024-12-24

申请号：US18452813

申请日：2023-08-21

Applicant: Global Life Sciences Solutions USA LLC

Inventor： Douglas Albagli ,  William A Hennessy

IPC: B01D67/00 ,  B01D69/02 ,  B01D71/64 ,  G03F7/00

Abstract: Porous liquid-filtering membranes having a repeatable distribution of pores of a small dimension are provided, as well as pillar templates that are used to produce such liquid filtering membranes. Also disclosed are methods of making and using the pillar templates to make porous liquid filtering membranes.